Cancer cell possesses numerous adaptations to resist the immune system response and
chemotherapy. One of the most significant properties of the neoplastic cells is the altered …

Many thousands of lipid species exist and their metabolism is interwoven via numerous
pathways and networks. These networks can also change in response to cellular …

Lipid transfer between cell membrane bilayers at contacts between the endoplasmic
reticulum (ER) and other membranes help to maintain membrane lipid homeostasis. We …

Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related
membrane aminophospholipids. In mammalian cells, PS is required for targeting and …

In eukaryotic cells, phosphatidylserine (PS) is synthesized in the endoplasmic reticulum
(ER) but is highly enriched in the plasma membrane (PM), where it contributes negative …

Paracrine and endocrine roles have increasingly been ascribed to extracellular vesicles
(EVs) generated by multicellular organisms. Central to the biogenesis, content, and function …

During the coronavirus disease 2019 (COVID‑19) pandemic, some patients with severe
COVID‑19 exhibited complications such as acute ischemic stroke (AIS), which was closely …

Electrostatic interactions with negatively charged membranes contribute to the subcellular
targeting of proteins with polybasic clusters or cationic domains. Although the anionic …

Recently, valorization of lignocellulosic biomass, the most abundantly available biomass
raw material on the Earth, to biofuels and chemicals has attracted great attention worldwide …

Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …