Association of multifocality with prognosis of papillary thyroid carcinoma: a systematic review and meta-analysis

H Kim, H Kwon, BI Moon - JAMA otolaryngology–head & neck …, 2021 - jamanetwork.com
Importance Multifocality is common in papillary thyroid carcinoma (PTC), but it is unclear
whether multifocal tumors are associated with tumor recurrence or cancer-specific survival …

Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations

A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) represents 80–90% of all differentiated
thyroid carcinomas. PTC has a high rate of gene fusions and mutations, which can influence …

NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake

YA Lee, H Lee, SW Im, YS Song, DY Oh… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Molecular characterization in pediatric papillary thyroid cancer (PTC),
distinct from adult PTC, is important for developing molecularly targeted therapies for …

Pediatric thyroid cancer: genetics, therapeutics and outcome

AJ Bauer - Endocrinology and Metabolism Clinics, 2020 - endo.theclinics.com
Most patients with thyroid cancer are asymptomatic at the time of diagnosis even in the
presence of regional or distant metastasis. More than 85% of childhood thyroid carcinomas …

Integrating molecular testing in the diagnosis and management of children with thyroid lesions

LY Ballester, SF Sarabia, H Sayeed… - Pediatric and …, 2016 - journals.sagepub.com
Thyroid nodules occur in 1–2% of children, and identifying which nodules are malignant is
often challenging. Cytologic evaluation facilitates the diagnosis of thyroid lesions (TLs), but …

Differentiated thyroid cancer in children and adolescents: long term outcome and risk factors for persistent disease

G Sapuppo, D Hartl, B Fresneau, J Hadoux, I Breuskin… - Cancers, 2021 - mdpi.com
Simple Summary Despite their excellent prognosis, pediatric differentiated thyroid cancers
(P-DTC) often undergo aggressive treatment due to the advanced disease presentation …

Genetic alterations landscape in paediatric thyroid tumours and/or differentiated thyroid cancer: Systematic review

MSA de Sousa, IN Nunes, YP Christiano… - Reviews in Endocrine …, 2024 - Springer
Differentiated thyroid cancer (DTC) is a rare disease in the paediatric population (≤ 18
years old. at diagnosis). Increasing incidence is reflected by increases in incidence for …

Survival trends in pediatric differentiated thyroid cancer: A middle eastern perspective

A Al-Ibraheem, M Al-Shammaa, AS Abdlkadir, F Istatieh… - Life, 2024 - mdpi.com
Pediatric Differentiated Thyroid Cancer (pedDTC) is a rare pediatric malignancy with an
increasing incidence over time. To date, there is a paucity of literature specifically …

Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas

YA Lee, SW Im, KC Jung, EJ Chung, CH Shin, JI Kim… - Thyroid, 2020 - liebertpub.com
Background: Pediatric thyroid cancer has characteristics that are distinct from adulthood
thyroid cancer. Due to its very low prevalence, little is known about the genetic …

Relationship of focally amplified long noncoding on chromosome 1 (FAL1) lncRNA with E2F transcription factors in thyroid cancer

S Jeong, J Lee, D Kim, MY Seol, WK Lee, JJ Jeong… - Medicine, 2016 - journals.lww.com
Recent functional genomic studies revealed that the oncogenic activity of focally amplified
lncRNA on chromosome 1 (FAL1, ENSG00000228126) contributes to tumor growth by p21 …