Metabolomics technology and bioinformatics

V Shulaev - Briefings in bioinformatics, 2006 - academic.oup.com
Metabolomics is the global analysis of all or a large number of cellular metabolites. Like
other functional genomics research, metabolomics generates large amounts of data …

Gas chromatography/mass spectrometry in metabolic profiling of biological fluids

KK Pasikanti, PC Ho, ECY Chan - Journal of Chromatography B, 2008 - Elsevier
One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …

[HTML][HTML] The human urine metabolome

S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Microbial contribution to the human metabolome: implications for health and disease

W Van Treuren, D Dodd - Annual Review of Pathology …, 2020 - annualreviews.org
The human gastrointestinal tract is home to an incredibly dense population of microbes.
These microbes employ unique strategies to capture energy in this largely anaerobic …

ISiCLE: a quantum chemistry pipeline for establishing in silico collision cross section libraries

SM Colby, DG Thomas, JR Nuñez, DJ Baxter… - Analytical …, 2019 - ACS Publications
High-throughput, comprehensive, and confident identifications of metabolites and other
chemicals in biological and environmental samples will revolutionize our understanding of …

Quantitative metabolic profiling based on gas chromatography.

SC Gates, CC Sweeley - Clinical chemistry, 1978 - academic.oup.com
The quantitative metabolic profiles of volatilizable components of human biological fluids,
particularly urinary organic acids, is reviewed, with emphasis on the use of gas …

Comprehensive targeted metabolomic assay for urine analysis

J Zheng, L Zhang, M Johnson, R Mandal… - Analytical …, 2020 - ACS Publications
Among all the human biological fluids used for disease biomarker discovery or clinical
chemistry, urine stands out. It can be collected easily and noninvasively, it is readily …

Gas-chromatographic method of analysis for urinary organic acids. I. Retention indices of 155 metabolically important compounds.

K Tanaka, DG Hine, A West-Dull, TB Lynn - Clinical Chemistry, 1980 - academic.oup.com
Gas-chromatographic retention indices are given, in terms of methylene units, for 155
metabolically important compounds (mostly organic acids) as trimethylsilyl derivatives on …

Mass spectrometry strategies for clinical metabolomics and lipidomics in psychiatry, neurology, and neuro-oncology

PL Wood - Neuropsychopharmacology, 2014 - nature.com
Metabolomics research has the potential to provide biomarkers for the detection of disease,
for subtyping complex disease populations, for monitoring disease progression and therapy …

Metabolomics: an integral technique in systems biology

W Weckwerth - Bioanalysis, 2010 - Taylor & Francis
Metabolomics is the unbiased identification and state-specific quantification of all
metabolites in a cell, tissue or whole organism, and has developed rapidly into one of the …