NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in
dendritic cells and macrophages and acts as a constituent of the inflammasome. This protein …

The activation of TNF receptors can lead to cell death with a mechanism of cell necrosis
regulated genetically and distinct from apoptosis which is defined as necroptosis …

Neuroinflammation is associated with many neurodegenerative diseases. Abnormal
activation of microglial cells in the central nervous system (CNS) is a major characteristic of …

Social anxiety disorder is a common psychiatric condition that severely affects individual
quality of life and is a significant societal burden. Although many risk factors for social …

Background Stroke is one of the major diseases that endangers human health. It is widely
reported that enriched environment (EE) can improve the neurological function in different …

Ischemic stroke (IS) is a leading cause of disability, morbidity, and mortality globally. Aging
affects immune function and contributes to poor outcomes of IS in elderly individuals …

Alzheimer's disease (AD) is a geriatric disease with the morbidity and mortality continuing to
grow, partly due to the aging of the world population. As one of the most common types of …

Objective The study aimed to explore the miRNA and mRNA biomarkers in post-stroke
depression (PSD) and to develop a miRNA–mRNA regulatory network to reveal its potential …

Currently, the effect and molecular mechanism of calycosin, the main active ingredient of
Qinshi Simiao San, which can alleviate chronic prostatitis (CP), on CP remain unclear. This …

Purpose: The aim is to investigate the effect of toludesvenlafaxine (Tdv), a reuptake inhibitor
of serotonin, norepinephrine, and dopamine, on the neurological function in cerebral …