We have performed a systematic review of studies reporting on the renal effects of SGLT2
inhibitors in rodent models of diabetes. In 105 studies, SGLT2 inhibitors improved not only …

Hypertensive nephropathy (HTN) is a common complication of hypertension. Although
various agents for treatment of hypertension exert significant effects, there is currently no …

Diabetic nephropathy (DN) is a serious complication in patients with diabetes, whose
expansion process is closely related to oxidative stress caused by hyperglycemia. Herein …

Antioxidants given concurrently with chemotherapy offer an effective strategy for reducing
the negative effects of the drug. One remaining obstacle to the use of doxorubicin (DOX) in …

Liver fibrosis is considered an epidemic health problem due to different insults that lead to
death. Dapagliflozin (DAPA), a sodium-glucose cotransporter-2 (SGLT2) inhibitor, is one of …

Background Renal diseases have a significant negative impact on human health and the
quality of life. Renal ischemia/reperfusion (I/R) injury is considered as one of the leading …

Zusammenfassung Hintergrund Durch den Einfluss des Geschlechts kommt es zu
pathophysiologischen Variationen, die unter anderem die Entstehung und den …

Among the most typical reasons of end-stage renal disease (ESRD) is diabetic nephropathy
(DN), which is also rated as a major microvascular complication of diabetes mellitus. The …

Aim and Objectives: The aim of the study was to evaluate the clinical outcomes of
dapagliflozin in DKD and to check the complications and quality of life of the patients after …

Diabetes mellitus (DM) is a multifaceted disorder that disrupts the body's overall metabolic
equilibrium, giving rise to various organ-related complications such as cardiovascular …