We conducted systematic reviews of predefined clinical questions and used the Grading of
Recommendations, Assessment, Development and Evaluations approach to develop …

Background & Aims Gastrointestinal diseases account for considerable health care use and
expenditures. We estimated the annual burden, costs, and research funding associated with …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Upper gastrointestinal bleeding (UGIB) continues to be a common gastrointestinal
emergency that carries significant morbidity and mortality. The epidemiology of UGIB has …

Acute lower gastrointestinal bleeding (LGIB) is a common reason for hospitalization in the
United States and is associated with significant utilization of hospital resources, as well as …

Gastrointestinal tract perforation is a full-thickness injury that causes bleeding and fatal
infection of the peritoneum. This condition worsens in an acidic gastric environment which …

Patient Blood Management (PBM) has been increasingly recognized as a fundamental
element of good clinical practice in transfusion. The importance of implementing effective …

Upper gastrointestinal bleeding is a common emergency presentation requiring prompt
resuscitation and management. Peptic ulcers are the most common cause of the condition …

Introduction Over the last decade, tranexamic acid (TXA) has been incorporated into
treatment algorithms for a multitude of emergent conditions and the evidence surrounding its …

Background & Aims Current guidelines vary as to their recommendations addressing the
role of hemostatic powders when managing patients with malignant gastrointestinal (GI) …