Age of insomnia onset correlates with a reversal of default mode network and supplementary motor cortex connectivity

E Santarnecchi, C Del Bianco, I Sicilia, D Momi… - Neural …, 2018 - Wiley Online Library
Insomnia might occur as result of increased cognitive and physiological arousal caused by
acute or long acting stressors and associated cognitive rumination. This might lead to …

Bidirectional relationships between sleep and amyloid-beta in the hippocampus

J Dufort-Gervais, V Mongrain, J Brouillette - Neurobiology of Learning and …, 2019 - Elsevier
Alzheimer's disease (AD) is a debilitating neurodegenerative disease characterized by
progressive hippocampal-dependent explicit memory deficits that begin at the onset of the …

Chronic sleep disturbances alters sleep structure and tau phosphorylation in AβPP/PS1 AD mice and their wild-type littermates

F Zhang, L Niu, R Zhong, S Li… - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: Emerging evidence indicates that sleep disorders are the common non-
cognitive symptoms of Alzheimer's disease (AD), and they may contribute to the …

Longitudinal associations between sleep duration and cognitive function in the elderly population in China: A 10‐year follow‐up study from 2005 to 2014

Q Zhang, Y Wu, E Liu - International Journal of Geriatric …, 2021 - Wiley Online Library
Objective Sleep duration is increasingly recognized as an important determinant of cognitive
function among elderly. However, longitudinal studies on the relationship between sleep …

Chronic sleep restriction increases soluble hippocampal Aβ-42 and impairs cognitive performance

KN Brice, CW Hagen, JL Peterman, JW Figg… - Physiology & …, 2020 - Elsevier
Currently, over 44 million people worldwide suffer from Alzheimer's disease (AD). A common
feature of AD is disrupted sleep. Sleep is essential for many psychological and physiological …

Sex and Sleep Disruption as Contributing Factors in Alzheimer's Disease

CE Johnson, MJ Duncan… - Journal of Alzheimer's …, 2024 - content.iospress.com
Alzheimer's disease (AD) affects more women than men, with women throughout the
menopausal transition potentially being the most under researched and at-risk group. Sleep …

Sleep deprivation exacerbates concussive head injury induced brain pathology: Neuroprotective effects of nanowired delivery of cerebrolysin with α-melanocyte …

A Sharma, DF Muresanu, A Ozkizilcik, ZR Tian… - Progress in brain …, 2019 - Elsevier
Sleep deprivation (SD) is very common in military personnel resulting in mental anomalies
and interfering with decision-making capabilities. Moreover during combat operation, these …

Sleep movements and respiratory coupling as a biobehavioral metric for early Alzheimer's disease in independently dwelling adults

S Khosroazad, CF Gilbert, JB Aronis, KM Daigle… - BMC geriatrics, 2023 - Springer
Introduction Sleep disorder is often the first symptom of age-related cognitive decline
associated with Alzheimer's disease (AD) observed in primary care. The relationship …

Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer's disease

M Yang, C Yan, D Ospondpant, L Wang… - Frontiers in …, 2024 - frontiersin.org
Background: The development of effective inhibitors that can inhibit amyloid β (A β) peptides
aggregation and promote neurite outgrowth is crucial for the possible treatment of …

Melatonin modulates TLR4/MyD88/NF-κB signaling pathway to ameliorate cognitive impairment in sleep-deprived rats

C Yin, M Zhang, L Cheng, L Ding, Q Lv… - Frontiers in …, 2024 - frontiersin.org
Sleep deprivation (SD) is commonplace in today's fast-paced society. SD is a severe public
health problem globally since it may cause cognitive decline and even neurodegenerative …