Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities

ME Lacouture, MJ Anadkat, RJ Bensadoun… - Supportive Care in …, 2011 - Springer
Background Epidermal growth factor receptor inhibitors (EGFRI) produce various
dermatologic side effects in the majority of patients, and guidelines are crucial for the …

Cutaneous adverse effects of targeted therapies: Part I: Inhibitors of the cellular membrane

JB Macdonald, B Macdonald, LE Golitz… - Journal of the American …, 2015 - Elsevier
There has been a rapid emergence of numerous targeted agents in the oncology community
in the last decade. This exciting paradigm shift in drug development lends promise for the …

[HTML][HTML] Prevention and management of dermatological toxicities related to anticancer agents: ESMO Clinical Practice Guidelines☆

ME Lacouture, V Sibaud, PA Gerber, C Van den Hurk… - Annals of …, 2021 - Elsevier
Highlights•This ESMO Clinical Practice Guideline provides recommendations on the
prevention/management of dermatological toxicities.•Authorship includes a multidisciplinary …

Recommendations for the prophylactic management of skin reactions induced by epidermal growth factor receptor inhibitors in patients with solid tumors

RD Hofheinz, G Deplanque, Y Komatsu… - The …, 2016 - academic.oup.com
Inhibition of the epidermal growth factor receptor (EGFR) is an established treatment that
extends patient survival across a variety of tumor types. EGFR inhibitors fall into two main …

[HTML][HTML] Management of egfr tki–induced dermatologic adverse events

B Melosky, NB Leighl, J Rothenstein, R Sangha… - Current …, 2015 - ncbi.nlm.nih.gov
Targeting the epidermal growth factor receptor (egfr) pathway has become standard practice
for the treatment of advanced non-small-cell lung cancer. Compared with chemotherapy …

Dermatologic events from EGFR inhibitors: the issue of the missing patient voice

B Tischer, R Huber, M Kraemer, ME Lacouture - Supportive care in cancer, 2017 - Springer
Purpose As epidermal growth factor receptor (EGFR) inhibitors are associated with a variety
of dermatologic adverse events (dAEs), the purpose of this study was to develop an …

Mechanism of lethal skin toxicities induced by epidermal growth factor receptor inhibitors and related treatment strategies

Y Li, R Fu, T Jiang, D Duan, Y Wu, C Li, Z Li… - Frontiers in …, 2022 - frontiersin.org
Epidermal growth factor receptor (EGFR) inhibitors are widely used to treat various types of
cancers such as non-small cell lung cancer, head and neck cancer, breast cancer …

Randomized, open-label trial evaluating the preventive effect of tetracycline on afatinib induced-skin toxicities in non-small cell lung cancer patients

O Arrieta, MT Vega-González, D López-Macías… - Lung Cancer, 2015 - Elsevier
Background Afatinib has shown long progression free survival and improvement in quality of
life in advanced Non-Small Cell Lung Cancer (NSCLC) patients. Although afatinib causes …

The impact of long-term antibiotic therapy of cutaneous adverse reactions to EGFR inhibitors in colorectal cancer patients

MM Mihai, A Ion, C Giurcăneanu, C Nițipir… - Journal of Clinical …, 2021 - mdpi.com
Colorectal cancer (CRC) is an important public health issue, in terms of incidence and
mortality, with approximately 1.8 million new cases reported worldwide in 2018 …

A review of the treatment options for skin rash induced by EGFR-targeted therapies: evidence from randomized clinical trials and a metaanalysis

J Ocvirk, S Heeger, P McCloud… - Radiology and oncology, 2013 - sciendo.com
Background. Agents targeting the epidermal growth factor receptor (EGFR) are amongst the
most extensively used of the targeted agents in the therapy of some of the most common …