Background Systemic inflammation is accepted as one of the pathophysiological
mechanisms of atrial fibrillation (AF). The role of inflammation has been shown previously …

The aim of this study was to investigate the association of five polymorphisms in the IL1A
and IL1B genes in Brazilian patients with primary open angle glaucoma (POAG). A case …

Methods and results: Study subjects comprised 62 OC patients and 126 healthy women.
Genotyping was done from genomic DNA obtained from blood simple by PCR. Positive …

Background: Chronic inflammation is associated with neoplasms and several types of
cancer. Therefore, polymorphisms in the inflammation-related genes could modify the …

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Genetic
variations in cytokine genes and their receptors lead to the severity of the disease. The …

There is a high need to improve the assessment of, especially non-genotoxic, carcinogenic
features of chemicals. We therefore explored a toxicogenomics-based approach using …

Background Development of sequential changes of mucous leading to gastric cancer and
familial cases of gastric cancer of intestinal type is widely connected with Helicobacter pylori …

Purpose. To validate microarray data on cytokeratin 13 (KRT13) and interleukin‐1 receptor
antagonist (IL1RN) expression in urothelial carcinoma of the urinary bladder (UCB) and to …

Background Host genetic susceptibility markers in immune response associated genes may
contribute to identify individuals with high risk of developing viral infection and viral …

Inflammation is a key event that is closely associated with the pathophysiology of frailty. The
relationship of genetic polymorphisms into inflammatory cytokines with frailty remains poorly …