Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by
Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any …

Infectious diseases have been evolving and re-evolving over the ages and causing
immense misery to humans. Among them, some have been prevented and eradicated, but …

Tuberculosis is one of the deadliest infectious diseases existing in the world since ancient
times and still possesses serious threat across the globe. Each year the number of cases …

TB continues to be a leading health threat despite the availability of powerful anti-TB drugs.
We report herein the design and synthesis of various hybrid molecules comprising pyrazine …

Currently, one third of the world's population is latently infected with Mycobacterium
tuberculosis (MTB), while 8.9–9.9 million new and relapse cases of tuberculosis (TB) are …

The emergence of antimicrobial resistance is arguably the most important threat to human
and animal health. The impacts of antimicrobial use can reach far from the site of …

Background In order to shorten the course of treatment and its effectiveness, it is essential to
gain an in-depth insight into the drug resistance mechanisms of Mycobacterium tuberculosis …

Regimens targeting Mycobacterium tuberculosis, the causative agent of tuberculosis (TB),
require long courses of treatment and a combination of three or more drugs. An increase in …

The chemotherapeutic potential of ruthenium (II) complexes has recently attracted
researchers' interest as antibacterial and anticancer agents. In this study, two novel half …