Inflammation, growth factors, and pulmonary vascular remodeling

PM Hassoun, L Mouthon, JA Barberà… - Journal of the american …, 2009 - jacc.org
Inflammatory processes are prominent in various types of human and experimental
pulmonary hypertension (PH) and are increasingly recognized as major pathogenic …

[HTML][HTML] Complement and viral pathogenesis

KA Stoermer, TE Morrison - Virology, 2011 - Elsevier
The complement system functions as an immune surveillance system that rapidly responds
to infection. Activation of the complement system by specific recognition pathways triggers a …

Pathology of pulmonary hypertension

RM Tuder, JC Marecki, A Richter, I Fijalkowska… - Clinics in chest …, 2007 - Elsevier
The secondary role of pathology in the present clinical management of pulmonary
hypertension (PH) reflects to some extent the limitations of the current understanding of the …

Finding undiagnosed patients with hepatitis C infection: an application of artificial intelligence to patient claims data

OM Doyle, N Leavitt, JA Rigg - Scientific reports, 2020 - nature.com
Hepatitis C virus (HCV) remains a significant public health challenge with approximately half
of the infected population untreated and undiagnosed. In this retrospective study, predictive …

[HTML][HTML] Inflammation, immunological reaction and role of infection in pulmonary hypertension

SS Pullamsetti, R Savai, W Janssen, BK Dahal… - Clinical Microbiology …, 2011 - Elsevier
Inflammation underlies a wide variety of physiological and pathological processes. Acute
inflammation is the initial response of the body to harmful stimuli. Chronic inflammation, by …

Albinterferon Alfa-2b was not inferior to pegylated interferon-α in a randomized trial of patients with chronic hepatitis C virus genotype 1

S Zeuzem, MS Sulkowski, EJ Lawitz, VK Rustgi… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: The current standard of care for patients with chronic hepatitis C
virus (HCV) genotype 1 is once-weekly pegylated interferon-α (Peg-IFNα) plus daily ribavirin …

Utilization of complement receptors in immune cell–microbe interaction

S Lukácsi, B Mácsik‐Valent, Z Nagy‐Baló… - FEBS …, 2020 - Wiley Online Library
The complement system is a major humoral component of immunity and is essential for the
fast elimination of pathogens invading the body. In addition to its indispensable role in …

Albinterferon Alfa-2b was not inferior to pegylated interferon-α in a randomized trial of patients with chronic hepatitis C virus genotype 2 or 3

DR Nelson, Y Benhamou, WL Chuang, EJ Lawitz… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: A phase 3 active-controlled study was conducted to assess the
efficacy/safety of albinterferon alfa-2b (albIFN), a novel, long-acting, genetic fusion …

Viral infection and pulmonary hypertension: is there an association?

CD Cool, NF Voelkel, T Bull - Expert review of respiratory medicine, 2011 - Taylor & Francis
Pulmonary arterial hypertension (PAH) may be idiopathic, familial or associated with various
disease processes. The vascular lesions common to all are the plexiform lesions. It is well …

Gender-specific disease trajectories prior to the onset of COPD allow individualized screening and early intervention

M Hagmann, F Baty, F Rassouli, MT Maeder… - Plos one, 2023 - journals.plos.org
Background Nation-wide hospitalization databases include diagnostic information at the
level of an entire population over an extended period of time. Comorbidity network and early …