Evidence suggests that mitochondrial metabolism may play a key role in controlling cancer
cells life and proliferation. Recent evidence also indicates how the altered contribution of …

Hypoxia is a persistent physiological feature of many different solid tumors and a key driver
of malignancy, and in recent years, it has been recognized as an important target for cancer …

Introduction. This article provides an overview of the potential use of ozone as an adjuvant
during cancer treatment. Methods. We summarize the findings of the most relevant …

In the last sixty years, publications in reputed journals have shown the preclinical positive
effect of ozone gas in cancer cells. However, the translation of these results into clinical …

Simple Summary Pancreatic cancer (PC) is related to lifestyle risks, chronic inflammation,
and germline mutations. Surgical resection and adjuvant chemotherapy are the main …

Oxygenation conditions are crucial for growth and tumor progression. Recent data suggests
a decrease in cancer cell proliferation occurring after exposure to normobaric hyperoxia …

Background Growing evidence suggests that ozone (O 3) protects the host against
pathological conditions mediated by reactive oxygen species by increasing the activity of …

Cold atmospheric plasmas and plasma-treated solutions (PTSs) have emerged as
promising approaches in cancer treatment because of their tumor-selective actions. While …

Despite progress in surgery and radiochemotherapy, the prognosis of glioblastoma (GB)
remains poor. GB cells exhibit a preference for hypoxia to maintain their tumor‑forming …

Ozone (O 3) gas is the triatomic state of oxygen and it is used as a disinfection agent due to
its strong oxidizing effect, since its discovery in the mid-nineteenth century. Ozone therapy is …