A key challenge in the clinical management and cause of treatment failure of prostate cancer
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …

Microfluidics is an interdisciplinary field that encompasses both science and engineering,
which aims to design and fabricate devices capable of manipulating extremely low volumes …

The approval of anticancer therapeutic strategies is still slowed down by the lack of models
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …

The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged
as a powerful approach in cancer research and drug development. This review provides an …

The maintenance of body homeostasis relies heavily on physiological barriers. Dysfunction
of these barriers can lead to various pathological processes, including increased exposure …

Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Microarrays are powerful tools for high-throughput bioassays that can extract information
from tens of thousands of micro-spots consisting of biomolecules. This information is …

Nonalcoholic fatty liver disease (NAFLD) begins with benign steatosis caused by ectopic
storage of triacylglycerols in the liver. Persistent steatosis, in combination with other genetic …

With the development of microfluidic technology, tumor-on-chip models have gradually
become a new tool for the study of breast cancer because they can simulate more key …

The continued rise in metabolic diseases such as obesity and type 2 diabetes mellitus poses
a global health burden, necessitating further research into factors implicated in the onset …