Gut microbial molecules in behavioural and neurodegenerative conditions

BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

[HTML][HTML] Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses

N Yuan, Y Chen, Y Xia, J Dai, C Liu - Translational psychiatry, 2019 - nature.com
Inflammation is a natural defence response of the immune system against environmental
insult, stress and injury, but hyper-and hypo-inflammatory responses can trigger diseases …

[HTML][HTML] Hesperetin, a citrus flavonoid, attenuates LPS-induced neuroinflammation, apoptosis and memory impairments by modulating TLR4/NF-κB signaling

T Muhammad, M Ikram, R Ullah, SU Rehman, MO Kim - Nutrients, 2019 - mdpi.com
Glial activation and neuroinflammation play significant roles in apoptosis as well as in the
development of cognitive and memory deficits. Neuroinflammation is also a critical feature in …

Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis

Q Liu, Y Xi, Q Wang, J Liu, P Li, X Meng, K Liu… - Brain, Behavior, and …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
cognitive deficits and psychiatric symptoms. The gut microbiota-brain axis plays a pivotal …

[HTML][HTML] Long-term cognitive dysfunction in cancer survivors

Z Országhová, M Mego, M Chovanec - Frontiers in molecular …, 2021 - frontiersin.org
Cancer-related cognitive impairment (CRCI) is a frequent side effect experienced by an
increasing number of cancer survivors with a significant impact on their quality of life …

[HTML][HTML] Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain

A Khan, T Ali, SU Rehman, MS Khan, SI Alam… - Frontiers in …, 2018 - frontiersin.org
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

[HTML][HTML] Phosphatidylserine, inflammation, and central nervous system diseases

X Ma, X Li, W Wang, M Zhang, B Yang… - Frontiers in aging …, 2022 - frontiersin.org
Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is
abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple …

PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)

AG Horti, R Naik, CA Foss, IL Minn… - Proceedings of the …, 2019 - National Acad Sciences
While neuroinflammation is an evolving concept and the cells involved and their functions
are being defined, microglia are understood to be a key cellular mediator of brain injury and …

[HTML][HTML] Cholinergic modulation of glial function during aging and chronic neuroinflammation

R Gamage, I Wagnon, I Rossetti, R Childs… - Frontiers in Cellular …, 2020 - frontiersin.org
Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

[HTML][HTML] The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer's Pathogenesis via Specific Pathways

H Wu, W Qiu, X Zhu, X Li, Z Xie, I Carreras… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's Disease (AD) is the most common form of dementia in older adults and has a
devastating impact on the patient's quality of life, which creates a significant socio-economic …