Advances in the diagnosis and management of well-differentiated neuroendocrine neoplasms

J Hofland, G Kaltsas, WW de Herder - Endocrine Reviews, 2020 - academic.oup.com
Neuroendocrine neoplasms constitute a diverse group of tumors that derive from the
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …

Consensus on biomarkers for neuroendocrine tumour disease

K Oberg, IM Modlin, W De Herder, M Pavel… - The Lancet …, 2015 - thelancet.com
Management of neuroendocrine neoplasia represents a clinical challenge because of its
late presentation, lack of treatment options, and limitations in present imaging modalities …

The North American neuroendocrine tumor society consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors

TR Halfdanarson, JR Strosberg, L Tang, AM Bellizzi… - Pancreas, 2020 - journals.lww.com
This article is the result of the North American Neuroendocrine Tumor Society consensus
conference on the medical management of pancreatic neuroendocrine tumors from July 19 …

[HTML][HTML] A meta-analysis of the accuracy of a neuroendocrine tumor mRNA genomic biomarker (NETest) in blood

K Öberg, A Califano, JR Strosberg, S Ma, U Pape… - Annals of …, 2020 - Elsevier
Background The lack of an accurate blood biomarker in neuroendocrine tumor (NET)
disease has hindered management. The advance of genomic medicine and the …

[HTML][HTML] Chromogranin A as circulating marker for diagnosis and management of neuroendocrine neoplasms: more flaws than fame

V Marotta, MC Zatelli, C Sciammarella… - Endocrine-related …, 2018 - erc.bioscientifica.com
Owing to the heterogeneity of neuroendocrine neoplasms (NENs), the availability of reliable
circulating markers is critical for improving diagnostics, prognostic stratification, follow-up …

Neuroendocrine neoplasia of the gastrointestinal tract revisited: towards precision medicine

G Rindi, B Wiedenmann - Nature Reviews Endocrinology, 2020 - nature.com
Over the past 5 years, a number of notable research advances have been made in the field
of neuroendocrine cancer, specifically with regard to neuroendocrine cancer of the …

Circulating transcript analysis (NETest) in GEP-NETs treated with somatostatin analogs defines therapy

JB Ćwikła, L Bodei, A Kolasinska-Ćwikła… - The Journal of …, 2015 - academic.oup.com
Context: Early and precise delineation of therapeutic responses are key issues in
neuroendocrine neoplasm/tumor management. Imaging is currently used but exhibits …

Long-term follow-up and role of FDG PET in advanced pancreatic neuroendocrine patients treated with 177Lu-D OTATATE

M Sansovini, S Severi, A Ianniello, S Nicolini… - European journal of …, 2017 - Springer
Abstract Purpose Lu-DOTATATE (Lu-PRRT) is a valid therapeutic option in differentiated
pancreatic neuroendocrine tumors (P-NETs). FDG PET seems to be an important prognostic …

[HTML][HTML] A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management

K Oberg, E Krenning, A Sundin, L Bodei… - Endocrine …, 2016 - ec.bioscientifica.com
The complexity of the clinical management of neuroendocrine neoplasia (NEN) is
exacerbated by limitations in imaging modalities and a paucity of clinically useful …

NET blood transcript analysis defines the crossing of the clinical rubicon: when stable disease becomes progressive

M Pavel, H Jann, V Prasad, I Drozdov, IM Modlin… - …, 2016 - karger.com
Background/Aims: A key issue in gastroenteropancreatic neuroendocrine tumors (GEP-
NETs) is early identification and prediction of disease progression. Clinical evaluation and …