Abstract The rapidly spreading Coronavirus Disease (COVID-19) pandemic, caused by the
severe acute respiratory syndrome coronavirus (SARS-CoV-2), represents an …

Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial
effects, the drug has interesting biochemical properties that might be applied against some …

Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …

Chloroquine (CQ) and its hydroxyl analogue hydroxychloroquine (HCQ) are weak bases
with a half-century long use as antimalarial agents. Apart from this antimalarial activity, CQ …

Understanding the SARS-CoV-2 virus' pathways of infection, virus–host–protein interactions,
and mechanisms of virus-induced cytopathic effects will greatly aid in the discovery and …

Pyridine and pyrimidine derivatives have received great interest in recent pharmacological
research, being effective in the treatment of various malignancies, such as myeloid …

ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is having serious consequences on …

SARS-CoV-02 is a new type of coronavirus capable of rapid transmission and causing
severe clinical symptoms; much of which has unknown biological etiology. It has prompted …

COVID-19, a pandemic of the 21st century caused by novel coronavirus SARS-CoV-2 was
originated from China and shallowed world economy and human resource. The medical …

Chikungunya virus (CHIKV) is a mosquito-transmitted Alphavirus that causes in humans an
acute infection characterized by polyarthralgia, fever, myalgia, and headache. Since 2005 …