Natural coumarins: exploring the pharmacological complexity and underlying molecular mechanisms
J Sharifi-Rad, N Cruz-Martins… - Oxidative Medicine …, 2021 - Wiley Online Library
Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …
[HTML][HTML] Coumarin: A natural, privileged and versatile scaffold for bioactive compounds
A Stefanachi, F Leonetti, L Pisani, M Catto, A Carotti - Molecules, 2018 - mdpi.com
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies
Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …
investigation to assess their potential therapeutic significance. It possesses immeasurable …
Review on natural coumarin lead compounds for their pharmacological activity
KN Venugopala, V Rashmi… - BioMed research …, 2013 - Wiley Online Library
Coumarin (2H‐1‐benzopyran‐2‐one) is a plant‐derived natural product known for its
pharmacological properties such as anti‐inflammatory, anticoagulant, antibacterial …
pharmacological properties such as anti‐inflammatory, anticoagulant, antibacterial …
Targeting Nrf2/Keap1 signaling pathway by bioactive natural agents: Possible therapeutic strategy to combat liver disease
Background Nuclear factor erythroid 2-related factor (Nrf2), a stress-activated transcription
factor, has been documented to induce a defense mechanism against oxidative stress …
factor, has been documented to induce a defense mechanism against oxidative stress …
[HTML][HTML] Coumarins as fungal metabolites with potential medicinal properties
OM Tsivileva, OV Koftin, NV Evseeva - Antibiotics, 2022 - mdpi.com
Coumarins are a structurally varied set of 2 H-chromen-2-one compounds categorized also
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …
Multi-spectroscopic and molecular modelling studies on the interaction of esculetin with calf thymus DNA
Understanding the interaction of small molecules with DNA has become an active research
area at the interface between chemistry, molecular biology and medicine. Plant derived …
area at the interface between chemistry, molecular biology and medicine. Plant derived …
Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency
A Lichota, L Gwozdzinski, K Gwozdzinski - European Journal of Medicinal …, 2019 - Elsevier
The term varicose vein refers to the twisted and swollen vein visible under the skin surface
which occurs most commonly in the leg. Epidemiological studies report a varying …
which occurs most commonly in the leg. Epidemiological studies report a varying …
[HTML][HTML] Targeting mammalian 5-lipoxygenase by dietary phenolics as an anti-inflammatory mechanism: A systematic review
JA Giménez-Bastida, A Gonzalez-Sarrias… - International Journal of …, 2021 - mdpi.com
5-Lipoxygenase (5-LOX) plays a key role in inflammation through the biosynthesis of
leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly) …
leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly) …
茵陈的化学成分和药理作用研究进展
曹锦花 - 沈阳药科大学学报, 2013 - cqvip.com
目的对茵陈药材在化学成分和药理作用方面的研究进行综述. 方法通过系统的文献调研,
以近年来的50 余篇中外文文献为依据对茵陈的化学成分和药理作用进行归纳总结 …
以近年来的50 余篇中外文文献为依据对茵陈的化学成分和药理作用进行归纳总结 …