Evaluation of the diagnostic accuracy of FAPI PET/CT in oncologic studies: systematic review and metaanalysis
G Wass, K Clifford… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Fibroblast-activation protein is a promising target for oncologic molecular imaging. Studies
show that fibroblast activation protein inhibitor (FAPI) radiotracers are accurate diagnostics …
show that fibroblast activation protein inhibitor (FAPI) radiotracers are accurate diagnostics …
From basic research to clinical application: targeting fibroblast activation protein for cancer diagnosis and treatment
Z Zhang, J Tao, J Qiu, Z Cao, H Huang, J Xiao… - Cellular Oncology, 2024 - Springer
Purpose This study aims to review the multifaceted roles of a membrane protein named
Fibroblast Activation Protein (FAP) expressed in tumor tissue, including its molecular …
Fibroblast Activation Protein (FAP) expressed in tumor tissue, including its molecular …
Advances in nuclear medicine-based molecular imaging in head and neck squamous cell carcinoma
D Li, X Li, J Zhao, F Tan - Journal of Translational Medicine, 2022 - Springer
Head and neck squamous cell carcinomas (HNSCCs) are often aggressive, making
advanced disease very difficult to treat using contemporary modalities, such as surgery …
advanced disease very difficult to treat using contemporary modalities, such as surgery …
Interobserver agreement rates on fibroblast activation protein inhibitor–directed molecular imaging and therapy
SE Serfling, PE Hartrampf, Y Zhi, T Higuchi… - Clinical nuclear …, 2022 - journals.lww.com
Objectives Fibroblast activation protein (FAP) has emerged as a novel target for FAP
inhibitor (FAPI)–directed molecular imaging and endoradiotherapy (ERT). We aimed to …
inhibitor (FAPI)–directed molecular imaging and endoradiotherapy (ERT). We aimed to …
Associations between normal organs and tumor burden in patients imaged with fibroblast activation protein inhibitor-directed positron emission tomography
A Kosmala, SE Serfling, N Dreher, T Lindner… - Cancers, 2022 - mdpi.com
Simple Summary Several radiolabeled fibroblast activation protein targeted inhibitors (FAPI)
have been developed for molecular imaging and therapy. A potential correlation of …
have been developed for molecular imaging and therapy. A potential correlation of …
Comparison of the detection performance between FAP and FDG PET/CT in various cancers: a systemic review and meta-analysis
WY Chang, NC Tseng, LY Chen… - Clinical Nuclear …, 2023 - journals.lww.com
Purpose 18 F-FDG is the dominant radiotracer in oncology; however, it has limitations. Novel
labeled fibroblast activation protein (FAP) radiotracers have been developed and published …
labeled fibroblast activation protein (FAP) radiotracers have been developed and published …
Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden and cardiovascular risk factors
A Kosmala, SE Serfling, K Michalski, T Lindner… - European Journal of …, 2023 - Springer
Purpose We aimed to assess prevalence, distribution, and intensity of in-vivo arterial wall
fibroblast activation protein (FAP) uptake, and its association with calcified plaque burden …
fibroblast activation protein (FAP) uptake, and its association with calcified plaque burden …
Therapeutic potential of antibody-drug conjugate-based therapy in head and neck cancer: a systematic review
Simple Summary Head and neck cancer (HNC) is a complex and extremely heterogeneous
disease that includes a wide variety of cancer subtypes. Despite notable advances in …
disease that includes a wide variety of cancer subtypes. Despite notable advances in …
Fibroblast activation protein alpha: Comprehensive detection methods for drug target and tumor marker
P Song, Q Pan, Z Sun, L Zou, L Yang - Chemico-Biological Interactions, 2022 - Elsevier
Fibroblast activation protein alpha (FAP-α, EC3. 4.2. B28), a type II transmembrane
proteolytic enzyme for the serine protease peptidase family. It is underexpressed in normal …
proteolytic enzyme for the serine protease peptidase family. It is underexpressed in normal …
Development of a fibroblast activation protein-targeted PET/NIR dual-modality probe and its application in head and neck cancer
D Li, X Li, J Li, Y Wang, F Tan, X Li - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Purpose: The combination of near-infrared (NIR) and positron emission tomography (PET)
imaging presents an opportunity to utilize the benefits of dual-modality imaging for tumor …
imaging presents an opportunity to utilize the benefits of dual-modality imaging for tumor …