Recent topics in fibroblast activation protein inhibitor-PET/CT: clinical and pharmacological aspects

Y Nakamoto, S Baba, H Kaida, O Manabe… - Annals of Nuclear …, 2024 - Springer
Recently, positron emission tomography (PET) with fibroblast activation protein inhibitor
(FAPI) has gained significant attention as an advanced tumor diagnostic imaging tool. FAPI …

Radiation Therapy Planning Using Fibroblast Activation Protein Inhibitor

SA Koerber - PET clinics, 2023 - pet.theclinics.com
The use of high-energy rays, alone or in combination with further treatment modalities such
as chemotherapy, has been a very effective tool for treating cancer for more than 120 years …

Quarter Century Positron Emission Tomography/Computed Tomography Transformation of Oncology: Head and Neck Cancer

RM Subramaniam - PET clinics, 2024 - pet.theclinics.com
In July 2001, the United States Center for Medicare and Medicaid Services approved
reimbursement for PET imaging for evaluating diagnosis, initial staging, and restaging for 6 …

Clinical applications of fibroblast activation protein‐targeted theranostics in oncologic and nononcologic disease: Current status and future directions

H Fu, W Guo, J Huang, H Wu, H Chen - iRADIOLOGY, 2023 - Wiley Online Library
Quinoline‐based fibroblast activation protein (FAP) inhibitor (FAPI)‐based positron emission
tomography (PET) imaging and radioligand therapy (RLT) are being investigated for use in a …

Diagnostic Accuracy of 68Ga-FAPI Versus 18F-FDG PET in Patients with Various Malignancies

N Hirmas, R Hamacher, M Sraieb… - Journal of Nuclear …, 2024 - Soc Nuclear Med
To assess the diagnostic accuracy of 68Ga-labeled fibroblast activation protein inhibitor
(FAPI) and 18F-labeled FDG PET for the detection of various tumors, we performed a head …

Role of 18F-FDG PET/CT in Head and Neck Squamous Cell Carcinoma: Current Evidence and Innovative Applications

C Caldarella, M De Risi, M Massaccesi, F Miccichè… - Cancers, 2024 - mdpi.com
Simple Summary Among head–neck tumors, squamous cell carcinoma is the most frequent
histotype and includes a range of malignancies with different sites of origin as well as …

Evaluating the Patterns of FAPI Uptake in the Shoulder Joint: a Preliminary Study Comparing with FDG Uptake in Oncological Studies

Y Matsusaka, RA Werner, SE Serfling, AK Buck… - Molecular Imaging and …, 2024 - Springer
Background Fibroblast activation protein inhibitor (FAPI) targeting PET has been introduced
as a novel molecular imaging modality for visualizing cancer-associated fibroblasts. There …

Fibroblast Activation Protein Inhibitor PET Imaging in Head and Neck Cancer.

M Röhrich - PET clinics, 2023 - europepmc.org
68 Ga-fibroblast activation protein inhibitor (FAPI)-PET is highly promising for head and neck
cancers including oral squamous cell carcinomas, hypopharynx carcinomas, adenoid cystic …

靶向成纤维细胞激活蛋白放射性药物在恶性肿瘤诊疗中的研究进展

李梦婷, 兰晓莉, 江大卫 - 药学进展, 2023 - pps.cpu.edu.cn
近年来, 靶向成纤维细胞激活蛋白(FAP) 的放射性药物在恶性肿瘤诊疗一体化领域备受关注.
FAP 是一种表达于肿瘤间质的蛋白质, 在肿瘤进展和转移过程中发挥着重要作用 …

[PDF][PDF] Associations between normal organs and tumor burden in patients imaged with fibroblast activation protein inhibitor-directed positron emission tomography …

A Kosmala, SE Serfling, N Dreher, T Lindner… - 2022 - opus.bibliothek.uni-augsburg.de
(1) Background: We aimed to quantitatively investigate [68Ga] Ga-FAPI-04 uptake in normal
organs and to assess a relationship with the extent of FAPI-avid tumor burden.(2) Methods …