Understanding chronic venous disease: a critical overview of its pathophysiology and medical management

MA Ortega, O Fraile-Martínez… - Journal of clinical …, 2021 - mdpi.com
Chronic venous disease (CVD) is a multifactorial condition affecting an important
percentage of the global population. It ranges from mild clinical signs, such as …

[HTML][HTML] Epigenetic age prediction in semen–marker selection and model development

A Pisarek, E Pośpiech, A Heidegger, C Xavier… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
DNA methylation analysis is becoming increasingly useful in biomedical research and
forensic practice. The discovery of differentially methylated sites (DMSs) that continuously …

The Circulating Biomarkers League: Combining miRNAs with Cell-Free DNAs and Proteins

K Felekkis, C Papaneophytou - International Journal of Molecular …, 2024 - mdpi.com
The potential of liquid biopsy for the prognosis and diagnosis of diseases is unquestionable.
Within the evolving landscape of disease diagnostics and personalized medicine, circulating …

Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis in C57BL/6 mice by down-regulating the DNA methylation levels of SREBP-2

Q Li, H Zhang, J Zou, H Mai, D Su, X Feng… - Food and Chemical …, 2019 - Elsevier
Bisphenol A (BPA), a major plasticizers that are commonly used for lining of beverage or
food-storage containers, has been shown to increase cholesterol levels with molecular …

Bioinformatics analysis of markers based on m6A related to prognosis combined with immune invasion of renal clear cell carcinoma

L Liu, M Zhuang, X Tu, C Li, H Liu… - Cell Biology …, 2023 - Wiley Online Library
The incidence rate of renal cell carcinoma (RCC) is about 3% of all adult cancers. Of these,
the Kidney clear cell renal cell carcinoma (KIRC) is the most common type, accounting for …

Brain microbiota in Huntington's disease patients

R Alonso, D Pisa, L Carrasco - Frontiers in Microbiology, 2019 - frontiersin.org
One of the most important challenges facing medical science is to better understand the
cause of neuronal pathology in neurodegenerative diseases. Such is the case for …

[HTML][HTML] LMP2A induces DNA methylation and expression repression of AQP3 in EBV-associated gastric carcinoma

J Wang, W Liu, X Zhang, Y Zhang, H Xiao, B Luo - Virology, 2019 - Elsevier
Abstract Epstein-Barr virus (EBV)-associated gastric carcinoma (EBVaGC) is a unique type
of gastric carcinomas that promoter hypermethylation of tumor-related genes is extremely …

Differences in DNA Methylation Between Disease-Resistant and Disease-Susceptible Chinese Tongue Sole (Cynoglossus semilaevis) Families

Y Xiu, C Shao, Y Zhu, Y Li, T Gan, W Xu… - Frontiers in …, 2019 - frontiersin.org
DNA methylation, the most widely studied and most well-understood epigenetic
modification, has been reported to play crucial roles in diverse processes. Although it has …

DNA Methylation Analysis Reveals Potential Mechanism in Takifugu rubripes Against Cryptocaryon irritans Infection

Y Xia, Y Yang, Y Liu, J Cheng, Y Liu, C Li, P Liu - Marine Biotechnology, 2024 - Springer
Takifugu rubripes (T. rubripes) is a valuable commercial fish, and Cryptocaryon irritans (C.
irritans) has a significant impact on its aquaculture productivity. DNA methylation is one of …

[PDF][PDF] Transitioning from analysing methylation profiles in bulk populations of Colorectal cancer cells to methylation profiles of single cells

H O'Neill - University of Otago, 2021 - core.ac.uk
Colorectal cancer (CRC) is one of the leading causes of death by cancer in New Zealand,
largely due to metastasis of the primary tumour to secondary sites around the body. The …