[HTML][HTML] Mechanistic insights into the pharmacological significance of silymarin

K Wadhwa, R Pahwa, M Kumar, S Kumar, PC Sharma… - Molecules, 2022 - mdpi.com
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

[HTML][HTML] How cancer cells remodel lipid metabolism: strategies targeting transcription factors

DW Jeong, S Lee, YS Chun - Lipids in Health and Disease, 2021 - Springer
Reprogramming of lipid metabolism has received increasing recognition as a hallmark of
cancer cells because lipid dysregulation and the alteration of related enzyme profiles are …

[HTML][HTML] Protective effects of flavonoids against mitochondriopathies and associated pathologies: focus on the predictive approach and personalized prevention

L Koklesova, A Liskova, M Samec, K Zhai… - International Journal of …, 2021 - mdpi.com
Multi-factorial mitochondrial damage exhibits a “vicious circle” that leads to a progression of
mitochondrial dysfunction and multi-organ adverse effects. Mitochondrial impairments …

[HTML][HTML] Targeted delivery of silibinin via magnetic niosomal nanoparticles: potential application in treatment of colon cancer cells

G Shafiei, D Jafari-Gharabaghlou… - Frontiers in …, 2023 - frontiersin.org
Introduction: In recent years, various nanoparticles (NPs) have been discovered and
synthesized for the targeted therapy of cancer cells. Targeted delivery increases the local …

Deciphering the molecular pathways of saroglitazar: A dual PPAR α/γ agonist for managing metabolic NAFLD

D Ezhilarasan - Metabolism, 2024 - Elsevier
Saroglitazar (SARO), a dual peroxisome proliferator activated receptor (PPAR)-α/γ agonist,
has been used to treat metabolic diseases such as insulin resistance and diabetic …

Investigation of Proapoptotic Effect of Digera muricata Leaf Extract against the Skin Cancer Cell Line (B16-F10)

J Dhivyadharshini, P Elumalai… - Journal of …, 2021 - archive.sdpublishers.com
Introduction: Skin cancers, such as melanoma, basal cell carcinoma, and squamous cell
carcinoma, frequently begin as changes in the skin. Cancer research continues to focus on …

[PDF][PDF] Anticancer effect of digera muricata leaf Extract against Prostate Cancer Cell Lines

S Vidyashri, P Elumalai, S Raghunandhakumar… - J Pharm Anal, 2021 - academia.edu
Background: Prostate cancer has become a major health problem globally during the last
few decades. It is the second most frequently diagnosed cancer in men worldwide and the …

Acacia catechu seed extract provokes cytotoxicity via apoptosis by intrinsic pathway in HepG2 cells

L Thangavelu, RV Geetha, E Devaraj… - Environmental …, 2022 - Wiley Online Library
Abstract Acacia catechu Willd (Fabaceae) is a thorny tree widely distributed in India and
commonly used as traditional Ayurvedic medicine for various ailments. The current study …

[HTML][HTML] Silibinin induces oral cancer cell apoptosis and reactive oxygen species generation by activating the JNK/c-Jun pathway

H Zhang, H Kim, SY Kim, H Hai, E Kim, L Ma… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Oral cancer is one of the most prevalent malignant tumors worldwide. Silibinin
has been reported to exert therapeutic effects in various cancer models. However, its …

Identification of candidate target genes of oral squamous cell carcinoma using high-throughput RNA-Seq data and in silico studies of their interaction with naturally …

U Soni, A Singh, R Soni, SK Samanta… - Journal of …, 2023 - Taylor & Francis
Abstract Oral Squamous Cell Carcinoma (OSCC) accounts for more than 90% of all kinds of
oral neoplasms that develop in the oral cavity. It is a type of malignancy that shows high …