[HTML][HTML] Anti-rheumatoid drugs advancements: New insights into the molecular treatment of rheumatoid arthritis

RB Mrid, N Bouchmaa, H Ainani, R El Fatimy… - Biomedicine & …, 2022 - Elsevier
Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …

Bone‐targeted exosomes: strategies and applications

J Wang, X Li, S Wang, J Cui, X Ren… - Advanced healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

M2-type exosomes nanoparticles for rheumatoid arthritis therapy via macrophage re-polarization

H Li, Y Feng, X Zheng, M Jia, Z Mei, Y Wang… - Journal of Controlled …, 2022 - Elsevier
Imbalance between the activities of pro-inflammatory M1 and anti-inflammatory M2
macrophages in rheumatoid arthritis (RA) induces synovial inflammation and autoimmunity …

A Nanomedicine‐Enabled Ion‐Exchange Strategy for Enhancing Curcumin‐Based Rheumatoid Arthritis Therapy

J Yang, B Yang, J Shi - Angewandte Chemie International …, 2023 - Wiley Online Library
Curcumin (Cur) has been clinically used for rheumatoid arthritis treatment by the means of
reactive oxygen species (ROS) scavenging and immune microenvironment regulation …

[HTML][HTML] Innate immunity drives pathogenesis of rheumatoid arthritis

MI Edilova, A Akram, AA Abdul-Sater - Biomedical Journal, 2021 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease affecting∼ 1% of the general
population. This disease is characterized by persistent articular inflammation and joint …

[HTML][HTML] Identifying immune cell infiltration and effective diagnostic biomarkers in rheumatoid arthritis by bioinformatics analysis

S Zhou, H Lu, M Xiong - Frontiers in immunology, 2021 - frontiersin.org
Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder
characterized by inflammatory cell infiltration, leading to persistent synovitis and joint …

[HTML][HTML] Macrophage as a peripheral pain regulator

R Domoto, F Sekiguchi, M Tsubota, A Kawabata - Cells, 2021 - mdpi.com
A neuroimmune crosstalk is involved in somatic and visceral pathological pain including
inflammatory and neuropathic components. Apart from microglia essential for spinal and …

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway

G Ge, J Bai, Q Wang, X Liang, H Tao, H Chen… - Science China Life …, 2022 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

[HTML][HTML] The role of reactive oxygen species in the rheumatoid arthritis-associated synovial microenvironment

X Wang, D Fan, X Cao, Q Ye, Q Wang, M Zhang… - Antioxidants, 2022 - mdpi.com
Rheumatoid arthritis (RA) is an inflammatory disease that begins with a loss of tolerance to
modified self-antigens and immune system abnormalities, eventually leading to synovitis …

[HTML][HTML] Multifunctional nanoparticle-mediated combining therapy for human diseases

X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …