Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …

Nanozyme‐Based Regulation of Cellular Metabolism and Their Applications

Y Wang, X Jia, S An, W Yin, J Huang… - Advanced …, 2024 - Wiley Online Library
Metabolism is the sum of the enzyme‐dependent chemical reactions, which produces
energy in catabolic process and synthesizes biomass in anabolic process, exhibiting high …

Integrating Pt nanoparticles with carbon nanodots to achieve robust cascade superoxide dismutase-catalase nanozyme for antioxidant therapy

Y Zhang, W Gao, Y Ma, L Cheng, L Zhang, Q Liu… - Nano Today, 2023 - Elsevier
Nanozymes, nanomaterials with intrinsic enzyme mimetic activity, have emerged and been
used in a broad range of applications yet are constrained with limited catalytic efficiency …

A Nanomedicine‐Enabled Ion‐Exchange Strategy for Enhancing Curcumin‐Based Rheumatoid Arthritis Therapy

J Yang, B Yang, J Shi - Angewandte Chemie International …, 2023 - Wiley Online Library
Curcumin (Cur) has been clinically used for rheumatoid arthritis treatment by the means of
reactive oxygen species (ROS) scavenging and immune microenvironment regulation …

A multifunctional nanoparticle mitigating cytokine storm by scavenging multiple inflammatory mediators of sepsis

Z Li, Y Feng, S Zhang, T Li, H Li, D Wang, K Hao… - ACS …, 2023 - ACS Publications
Sepsis is a disease caused by infection, which is characterized by a dysregulated immune
response in the host and affects more than 30 million people worldwide each year …

RhRu Alloy‐Anchored MXene Nanozyme for Synergistic Osteosarcoma Therapy

Y Liang, C Liao, X Guo, G Li, X Yang, J Yu, J Zhong… - Small, 2023 - Wiley Online Library
Noble metal nanozymes hold promise in cancer therapy due to adjustable enzyme‐like
activities, unique physicochemical properties, etc. But catalytic activities of monometallic …

Natural polyphenolic nanodots for Alzheimer's disease treatment

P Yang, Q Huang, J Zhang, Y Li, H Gao… - Advanced …, 2024 - Wiley Online Library
The abnormal amyloid‐β accumulation is essential and obbligato in Alzheimer's disease
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …

Metal‐Based Nanozymes with Multienzyme‐Like Activities as Therapeutic Candidates: Applications, Mechanisms, and Optimization Strategy

D Li, D Dai, G Xiong, S Lan, C Zhang - Small, 2023 - Wiley Online Library
Most nanozymes in development for medical applications only exhibit single‐enzyme‐like
activity, and are thus limited by insufficient catalytic activity and dysfunctionality in complex …

Curcumin-based nanoformulations as an emerging therapeutic strategy for inflammatory lung diseases

AA Bhat, R Thapa, A Goyal… - Future Medicinal …, 2023 - Taylor & Francis
The main factor contributing to various fatal pulmonary diseases, including asthma,
pneumonia, pneumocystis, COPD, lung cancer and pulmonary fibrosis, is inflammation [1]. A …

Nanotechnology meets glioblastoma multiforme: Emerging therapeutic strategies

D Liu, X Dai, L Ye, H Wang, H Qian… - Wiley …, 2023 - Wiley Online Library
Glioblastoma multiforme (GBM) represents the most common and fatal form of primary
invasive brain tumors as it affects a great number of patients each year and has a median …