Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Animal models of hypertension: a scientific statement from the American Heart Association

LO Lerman, TW Kurtz, RM Touyz, DH Ellison… - …, 2019 - Am Heart Assoc
Hypertension is the most common chronic disease in the world, yet the precise cause of
elevated blood pressure often cannot be determined. Animal models have been useful for …

Brain insulin resistance and hippocampal plasticity: mechanisms and biomarkers of cognitive decline

M Spinelli, S Fusco, C Grassi - Frontiers in neuroscience, 2019 - frontiersin.org
In the last decade, much attention has been devoted to the effects of nutrient-related signals
on brain development and cognitive functions. A turning point was the discovery that brain …

Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature

N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

Biochemical and nutritional overview of diet-induced metabolic syndrome models in rats: what is the best choice?

E Rodríguez-Correa, I González-Pérez… - Nutrition & …, 2020 - nature.com
Metabolic syndrome (MS) is a condition that includes obesity, insulin resistance,
dyslipidemias among other, abnormalities that favors type 2 Diabetes Mellitus (T2DM) and …

[HTML][HTML] Managing obesity through natural polyphenols: A review

M Singh, T Thrimawithana, R Shukla, B Adhikari - Future Foods, 2020 - Elsevier
Obesity is a pervasive global health problem needing urgent research and regulatory
attention. Although synthetic anti-obesity drugs are available, they come with considerable …

Derivation of adult canine intestinal organoids for translational research in gastroenterology

L Chandra, DC Borcherding, D Kingsbury, T Atherly… - BMC biology, 2019 - Springer
Background Large animal models, such as the dog, are increasingly being used for studying
diseases including gastrointestinal (GI) disorders. Dogs share similar environmental …

Microplastic-induced gut microbiota and serum metabolic disruption in Sprague-Dawley rats

N Zhao, M Zhao, H Jin - Environmental Pollution, 2023 - Elsevier
Toxic effects of exposure to microplastics (MPs) on living organisms and humans have
attracted global concern. However, most previous studies exposed animals to only one type …

Non-nutritive sweeteners and their implications on the development of metabolic syndrome

I Liauchonak, B Qorri, F Dawoud, Y Riat, MR Szewczuk - Nutrients, 2019 - mdpi.com
Individuals widely use non-nutritive sweeteners (NNS) in attempts to lower their overall daily
caloric intake, lose weight, and sustain a healthy diet. There are insufficient scientific data …

[HTML][HTML] Placental structure in gestational diabetes mellitus

I Carrasco-Wong, A Moller, FR Giachini… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The placenta is a transitory organ, located between the mother and the foetus, which
supports intrauterine life. This organ has nutritional, endocrine and immunologic functions to …