Sympatho‐inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar–Kyoto rats

JC Balt, MJ Mathy, M Pfaffendorf… - Fundamental & …, 2003 - Wiley Online Library
Abstract Angiotensin II (Ang II) can enhance sympathetic neurotransmission by acting on
(AT1) receptors that are located on sympathetic nerve terminals. We investigated …

Chronic administration of losartan plus hydrochlorothiazide improves vascular status in young cardiomyopathic hamsters

MJ Crespo, WC De Mello - European journal of pharmacology, 2001 - Elsevier
The combination of an angiotensin II receptor antagonist and a thiazide has been used
extensively in the treatment of patients with overt heart failure. The effect of this combination …

Quantitative changes in pharmacodynamic parameters of noradrenaline in different rat aorta preparation: influence of endogenous EDRF

F Zonta, A Barbieri, M Reguzzoni… - Journal of autonomic …, 1998 - Wiley Online Library
The aim of the present study was to assess the role of endothelia cells in the modulation of
vasocontractile responses to noradrenaline in rat isolated aorta when cut as standard helical …

Losartan and captopril follow different mechanisms to decrease pressor responses in the pithed rat

H Yokoyama, S Minatoguchi, M Koshiji… - Clinical and …, 1997 - Wiley Online Library
We investigated the effects of losartan and captopril on noradrenaline (NA) release and
vascular reactivity to NA in the pithed rat. 2. The pressor responses to sympathetic nerve …

The pressor effect of NO synthase inhibition correlates to pre-existing systolic BP in the rat

HH Elayan, BP Kennedy, MG Ziegler - Autonomic Neuroscience, 2002 - Elsevier
A number of studies have found that the vasopressor effect of nitric oxide (NO) synthase
inhibition is small following treatment with hypotensive agents but is enhanced after …

Der Einfluss eines NO-Defizits auf die Transkription profibrotischer Proteine in der Lunge

B Brockhoff - 2019 - jlupub.ub.uni-giessen.de
Im Vorfeld dieser Studie war bereits bekannt, dass die Entstehung kardiovaskulärer
Erkrankungen im Allgemeinen sowie diverser Lungenerkrankungen im Speziellen, durch …

Sympathetic Interactions of AT1 Receptors

JC Balt, M Pfaffendorf - Angiotensin Vol. I, 2004 - Springer
The present chapter deals with the interaction between the renin-angiotensin system (RAS)
and the sympathetic nervous system (SNS). Numerous studies have shown that (locally …