Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Prescribing the frequency, duration, or volume of training is simple as these factors can be
altered by manipulating the number of exercise sessions per week, the duration of each …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Engaging in regular exercise results in a range of physiological adaptations offering benefits
for exercise capacity and health, independent of age, gender or the presence of chronic …

It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

Mitochondrial structures were probably observed microscopically in the 1840s, but the idea
of oxidative phosphorylation (OXPHOS) within mitochondria did not appear until the 1930s …

Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an
accessible, inexpensive therapeutic intervention that can improve mitochondrial …

New Findings What is the central question of this study? Exercise is known to promote
mitochondrial biogenesis in skeletal muscle, but what are the most relevant training …

Regular exercise is associated with pronounced health benefits. The molecular processes
involved in physiological adaptations to exercise are best understood in skeletal muscle …