Fatty acid metabolism-related genes are associated with flavor-presenting aldehydes in Chinese local chicken

X Yuan, H Cui, Y Jin, W Zhao, X Liu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Aldehydes are primary volatile organic compounds (VOCs) in local Chinese chicken meat
and contribute green grass, fatty, citrus, and bitter almond aromas to chicken meat. To …

Lipotoxicity-induced circGlis3 impairs beta cell function and is transmitted by exosomes to promote islet endothelial cell dysfunction

L Xiong, L Chen, L Wu, W He, D Chen, Z Peng, J Li… - Diabetologia, 2022 - Springer
Aims/hypothesis Lipotoxicity constitutes the major driving force for type 2 diabetes. Circular
RNAs (circRNAs) play important roles in regulating beta cell function and exosomes are …

Identification of functionally important miRNA targeted genes associated with child obesity trait in genome-wide association studies

M Song, J Yu, B Li, J Dong, J Gao, L Shang, X Zhou… - BMC genomics, 2022 - Springer
Background Genome-wide association studies (GWAS) have uncovered thousands of
genetic variants that are associated with complex human traits and diseases. miRNAs are …

m6A-mRNA reader YTHDF2 identified as a potential risk gene in autism with disproportionate megalencephaly

SS Nishizaki, NK Haghani, GN La, NAF Mariano… - medRxiv, 2022 - medrxiv.org
Among autistic individuals, a subphenotype of disproportionate megalencephaly (ASD-DM)
seen at three years of age is associated with co-occurring intellectual disability and poorer …

MicroRNA-322 overexpression reduces neural tube defects in diabetic pregnancies

G Wang, S Song, WB Shen, EA Reece… - American Journal of …, 2024 - Elsevier
Background Hyperglycemia from pregestational diabetes mellitus induces neural tube
defects in the developing fetus. Folate supplementation is the only effective way to prevent …

GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-κB Signalling and Is Positively Regulated by the m6A Reader YTHDF1

Z Ning, Z Wu, F Zhang, M Yang, Z Lu, B Yu, F Long… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the third most common cancer worldwide and
the second leading cause of cancer-related death. In this study, we aimed to determine the …

MicroRNA‑1226‑3p has a tumor‑promoting role in osteosarcoma

Y Li, D Song, T An, J Liu, Q Yang… - Oncology …, 2021 - spandidos-publications.com
Osteosarcoma is a malignant bone tumor that commonly occurs in young individuals. It
accounts for 10% of solid tumors in those who are 15‑19 years old. MicroRNA (miRNA/miR) …