[HTML][HTML] Lipotoxicity-induced circGlis3 impairs beta cell function and is transmitted by exosomes to promote islet endothelial cell dysfunction
L Xiong, L Chen, L Wu, W He, D Chen, Z Peng, J Li… - Diabetologia, 2022 - Springer
Aims/hypothesis Lipotoxicity constitutes the major driving force for type 2 diabetes. Circular
RNAs (circRNAs) play important roles in regulating beta cell function and exosomes are …
RNAs (circRNAs) play important roles in regulating beta cell function and exosomes are …
[HTML][HTML] Fatty acid metabolism-related genes are associated with flavor-presenting aldehydes in Chinese local chicken
X Yuan, H Cui, Y Jin, W Zhao, X Liu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Aldehydes are primary volatile organic compounds (VOCs) in local Chinese chicken meat
and contribute green grass, fatty, citrus, and bitter almond aromas to chicken meat. To …
and contribute green grass, fatty, citrus, and bitter almond aromas to chicken meat. To …
[HTML][HTML] Identification of functionally important miRNA targeted genes associated with child obesity trait in genome-wide association studies
Background Genome-wide association studies (GWAS) have uncovered thousands of
genetic variants that are associated with complex human traits and diseases. miRNAs are …
genetic variants that are associated with complex human traits and diseases. miRNAs are …
[HTML][HTML] MicroRNA‑1226‑3p has a tumor‑promoting role in osteosarcoma
Y Li, D Song, T An, J Liu, Q Yang… - Oncology …, 2021 - spandidos-publications.com
Osteosarcoma is a malignant bone tumor that commonly occurs in young individuals. It
accounts for 10% of solid tumors in those who are 15‑19 years old. MicroRNA (miRNA/miR) …
accounts for 10% of solid tumors in those who are 15‑19 years old. MicroRNA (miRNA/miR) …
MicroRNA-322 overexpression reduces neural tube defects in diabetic pregnancies
G Wang, S Song, WB Shen, EA Reece… - American Journal of …, 2024 - Elsevier
Background Hyperglycemia from pregestational diabetes mellitus induces neural tube
defects in the developing fetus. Folate supplementation is the only effective way to prevent …
defects in the developing fetus. Folate supplementation is the only effective way to prevent …
A Subphenotype-to-Genotype Approach Reveals Disproportionate Megalencephaly Autism Risk Genes
SS Nishizaki, NAF Mariano, GN La, JM Uribe-Salazar… - medRxiv, 2022 - medrxiv.org
Among autistic individuals, a subphenotype with brain enlargement disproportionate to
height (autism with disproportionate megalencephaly, or ASD-DM) seen at three years of …
height (autism with disproportionate megalencephaly, or ASD-DM) seen at three years of …
[HTML][HTML] GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-κB Signalling and Is Positively Regulated by the m6A Reader …
Z Ning, Z Wu, F Zhang, M Yang, Z Lu, B Yu, F Long… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the third most common cancer worldwide and
the second leading cause of cancer-related death. In this study, we aimed to determine the …
the second leading cause of cancer-related death. In this study, we aimed to determine the …