Just over a decade ago, a novel GABAergic input originating from a subpopulation of
external globus pallidus neurons known as Arkypallidal and projecting exclusively to the …

The brain is a remarkably complex organ responsible for a wide range of functions,
including the modulation of emotional states and movement. Neuronal circuits are believed …

In the classical model of the basal ganglia, direct pathway striatal projection neurons
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …

Most neuroeconomic research seeks to understand how value influences decision-making.
The influence of reward type is less well understood. We used functional magnetic …

Physical exercise (PE) may be the single most important and accessible lifestyle habit
throughout life, it inhibits the neuroinflammatory response and protects the brain against …

In patients with Parkinson's disease (PD), dopamine replacement therapy with dopamine
D2/D3 receptor agonists induces impairments in decision-making, including pathological …

The posterior medial (POm) thalamus is heavily interconnected with sensory and motor
circuitry and is likely involved in behavioral modulation and sensorimotor integration. POm …

The canonical basal ganglia model predicts that the substantia nigra pars reticulata (SNr)
and the globus pallidus externa (GPe) will have specific effects on locomotion: the SNr …

Understanding the neurocognitive mechanisms of the coordination of habitual and goal-
directed behaviors is particularly important, as impaired coordination will cause various …

Learned behaviors require the processing and transformation of sensory stimuli into motor
actions, a process known as sensorimotor integration. Disruption of this process is …