Adult stem cell niches for tissue homeostasis

G Mannino, C Russo, G Maugeri… - Journal of cellular …, 2022 - Wiley Online Library
Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

Revisiting lab-on-a-chip technology for drug discovery

P Neužil, S Giselbrecht, K Länge, TJ Huang… - Nature reviews Drug …, 2012 - nature.com
The field of microfluidics or lab-on-a-chip technology aims to improve and extend the
possibilities of bioassays, cell biology and biomedical research based on the idea of …

Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury

Q Sastourné-Arrey, M Mathieu, X Contreras… - Nature …, 2023 - nature.com
Fibro-adipogenic progenitors (FAPs) play a crucial role in skeletal muscle regeneration, as
they generate a favorable niche that allows satellite cells to perform efficient muscle …

Cell patterning technologies for organotypic tissue fabrication

B Guillotin, F Guillemot - Trends in biotechnology, 2011 - cell.com
Bottom-up tissue engineering technologies address two of the main limitations of top-down
tissue engineering approaches: the control of mass transfer and the fabrication of a …

An algorithm-based topographical biomaterials library to instruct cell fate

HV Unadkat, M Hulsman… - Proceedings of the …, 2011 - National Acad Sciences
It is increasingly recognized that material surface topography is able to evoke specific
cellular responses, endowing materials with instructive properties that were formerly …

Evolving roles of muscle-resident fibro-adipogenic progenitors in health, regeneration, neuromuscular disorders, and aging

M Theret, FMV Rossi, O Contreras - Frontiers in Physiology, 2021 - frontiersin.org
Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited
neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of …

Tunable supramolecular hydrogels for selection of lineage-guiding metabolites in stem cell cultures

EV Alakpa, V Jayawarna, A Lampel, KV Burgess… - Chem, 2016 - cell.com
Stem cells are known to differentiate in response to the chemical and mechanical properties
of the substrates on which they are cultured. Thus, supramolecular biomaterials with tunable …

Physical, Spatial, and Molecular Aspects of Extracellular Matrix of In Vivo Niches and Artificial Scaffolds Relevant to Stem Cells Research

M Akhmanova, E Osidak, S Domogatsky… - Stem cells …, 2015 - Wiley Online Library
Extracellular matrix can influence stem cell choices, such as self‐renewal, quiescence,
migration, proliferation, phenotype maintenance, differentiation, or apoptosis. Three aspects …

Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials

CJC Edwards-Gayle, IW Hamley - Organic & biomolecular chemistry, 2017 - pubs.rsc.org
Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and
biological applications. One of the main driving forces of self-assembly is molecular …

Laser-based direct-write techniques for cell printing

NR Schiele, DT Corr, Y Huang, NA Raof, Y Xie… - …, 2010 - iopscience.iop.org
Fabrication of cellular constructs with spatial control of cell location (±5 µm) is essential to
the advancement of a wide range of applications including tissue engineering, stem cell and …