[HTML][HTML] The roles of m6A methylation in cervical cancer: functions, molecular mechanisms, and clinical applications
Z Mao, B Wang, T Zhang, B Cui - Cell Death & Disease, 2023 - nature.com
Cervical cancer (CC) is a gynecological neoplasm with the highest incidence rate, primarily
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …
[HTML][HTML] Orchestral role of lipid metabolic reprogramming in T-cell malignancy
The immune function of normal T cells partially depends on the maneuvering of lipid
metabolism through various stages and subsets. Interestingly, T-cell malignancies also …
metabolism through various stages and subsets. Interestingly, T-cell malignancies also …
[HTML][HTML] The combined inhibition of autophagy and diacylglycerol acyltransferase-mediated lipid droplet biogenesis induces cancer cell death during acute amino acid …
Simple Summary In this study, the relationship between autophagy and lipid droplets in the
response of cancer cells to starvation was investigated. Under conditions of amino acid …
response of cancer cells to starvation was investigated. Under conditions of amino acid …
The role of BCL2L13 in Glioblastoma: Turning a need into a target
J Jacobs, R Iranpour, AB Behrooz… - … and Cell Biology, 2023 - cdnsciencepub.com
Glioblastoma (GBM) is the most common aggressive central nervous system cancer. GBM
has a high mortality rate, with a median survival time of 12–15 months after diagnosis. A …
has a high mortality rate, with a median survival time of 12–15 months after diagnosis. A …
[HTML][HTML] Maternal malic acid may ameliorate oxidative stress and inflammation in sows through modulating gut microbiota and host metabolic profiles during late …
M Chen, Y Zhao, S Li, Z Chang, H Liu, D Zhang… - Antioxidants, 2024 - mdpi.com
Sows suffer oxidative stress and inflammation induced by metabolic burden during late
pregnancy, which negatively regulates reproductive and lactating performances. We …
pregnancy, which negatively regulates reproductive and lactating performances. We …
[HTML][HTML] Pentacyclic Triterpenes from Olive Leaves Formulated in Microemulsion: Characterization and Role in De Novo Lipogenesis in HepG2 Cells
M Vasarri, D Degl'Innocenti, L Albonetti… - International Journal of …, 2023 - mdpi.com
Olea europaea L. leaves contain a wide variety of pentacyclic triterpenes (TTPs). TTPs
exhibit many pharmacological activities, including antihyperlipidemic effects. Metabolic …
exhibit many pharmacological activities, including antihyperlipidemic effects. Metabolic …
[HTML][HTML] The impact of menopause on cardiovascular aging: a comprehensive review of androgen influences
A Raj, S Chakole, S Agrawal, A Gupta, H Khekade… - Cureus, 2023 - ncbi.nlm.nih.gov
Menopause represents a critical life stage in women, characterized by hormonal changes
that significantly impact cardiovascular health. While the decline in estrogen levels has long …
that significantly impact cardiovascular health. While the decline in estrogen levels has long …
[HTML][HTML] Identification and validation of metabolism-related genes signature and immune infiltration landscape of rheumatoid arthritis based on machine learning
Z Guo, Y Ma, Y Wang, H Xiang, H Cui, Z Fan… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) causes irreversible joint damage, but the pathogenesis is
unknown. Therefore, it is crucial to identify diagnostic biomarkers of RA metabolism-related …
unknown. Therefore, it is crucial to identify diagnostic biomarkers of RA metabolism-related …
[HTML][HTML] Co-morbid intersections of cancer and cardiovascular disease and targets for natural drug action: Reprogramming of lipid metabolism
G Zhu, L Cao, J Wu, M Xu, Y Zhang, M Wu… - Biomedicine & …, 2024 - Elsevier
Cancer and cardiovascular diseases are major contributors to global morbidity and mortality,
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …
[HTML][HTML] Transcriptome and Metabolome Analyses Reveal the Mechanism of Corpus Luteum Cyst Formation in Pigs
J Dai, J Cai, T Zhang, M Pang, X Xu, J Bai, Y Liu, Y Qin - Genes, 2023 - mdpi.com
Corpus luteum cysts are a serious reproductive disorder that affects the reproductive
performance of sows. In this study, transcriptome and metabolome datasets of porcine …
performance of sows. In this study, transcriptome and metabolome datasets of porcine …