In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …

DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …

Aging is one of the critical factors to impair liver regeneration leading to a high incidence of
severe complications after hepatic surgery in the elderly population without any effective …

The heat shock protein 27 (Hsp27) has emerged as a principal factor of the castration-
resistant prostate cancer (CRPC) progression. Also, an antisense oligonucleotide (ASO) …

The mammalian DEAD‐box RNA helicase DDX5, its paralog DDX17, and their orthologs in
Saccharomyces cerevisiae and Drosophila melanogaster, namely Dbp2 and Rm62, define a …

Simple Summary Cancer-associated mortality largely depends on metastatic dissemination.
Metastasizing cancer cells exhibit drastic phenotypic changes, including the ability to …

Resveratrol shows potent anti-tumor therapeutic properties in various tumors. However, the
exact effect of resveratrol on osteosarcoma cells, especially cancer stem cells, remains …

There is increasing evidence indicating the significant role of DDX5 (also called p68), acting
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …

The DEAD-box RNA helicase DDX5 is a member of a family of highly conserved proteins
involved in gene-expression regulation and ATP-dependent RNA helicase activities …

Resveratrol, one of the major polyphenols found in red wine, is suggested to have a role as
a chemoprevention or chemotherapy agent in various human cancer models. Herein, we …