STUDY QUESTION What is the association between daily preconception-initiated low-dose
aspirin (LDA) treatment and very early pregnancy losses or euploid (chromosomally normal) …

We performed a meta-analysis to evaluate the risk of venous thromboembolism (VTE) in
pregnant women with essential thrombocythemia. Twenty-one trials and 756 pregnancies …

STUDY QUESTION What is the association between perceived stress during peri-
conception and early pregnancy and pregnancy loss among women who have experienced …

Objective To perform a meta‐analysis and meta‐regression of randomized controlled trials
(RCTs) to evaluate the impact of low‐dose aspirin (LDA) on perinatal outcome, independent …

Background Overt thyroid dysfunction has been associated with adverse obstetric outcomes.
However, less is known regarding subclinical hypothyroidism or thyroid autoimmunity and …

Problem What are the pregnancy outcomes after the OP timization of T hyroid function, Im
munity, and U terine M ilieu (OPTIMUM) treatment strategy in patients with repeated …

Context: Inflammation is linked to causes of infertility. Low-dose aspirin (LDA) may improve
reproductive success in women with chronic, low-grade inflammation. Objective: To …

OBJECTIVE: To evaluate complications and safety of preconception low-dose aspirin in
1,228 US women (2007–2011). METHODS: Evaluation of the safety of low-dose aspirin in …

Aspirin and heparin are widely used to reduce the risk of recurrent pregnancy loss in women
with antiphospholipid syndrome. This practice is based on only a few intervention studies …

Normal pregnancy is an immunotolerant state. Many factors, including environmental,
socioeconomic, genetic, and immunologic changes by infection and/or other causes of …