Background Platelet activation may play a role in the pathophysiology of placenta-mediated
obstetrical complications, as evidenced by the efficacy of aspirin in preventing preeclampsia …

Objective: The objective was to determine the effect of preconception-initiated daily low-
dose aspirin (LDA; 81 mg/day) treatment on time to pregnancy in women with a history of …

Introduction: There is recent evidence that prophylaxis with 150 mg of aspirin given before
14–16 weeks significantly reduces preeclampsia rates and may improve pregnancy …

Background Caffeine is the most frequently used psychoactive substance in the United
States and> 90% of reproductive-age women report some amount of intake daily. Despite …

BACKGROUND The daily use of low-dose aspirin may be a safe, widely available, and
inexpensive intervention for reducing the risk of preterm birth. Data on the potential side …

Maternal health and well-being refers to the physical, psychological, and emotional well-
being of women during pregnancy, childbirth, and the postnatal period, as well as the …

Background: Although fatty acids are involved in critical reproductive processes, the
relationship between specific fatty acids and fertility is uncertain. We investigated the …

Adequate development of the placenta is essential for optimal pregnancy outcome. Pre-
eclampsia (PE) is increasingly recognized to be a consequence of placental dysfunction and …

STUDY QUESTION Are insufficient 25-hydroxyvitamin D (25 (OH) D) concentrations, and
other markers of vitamin D metabolism, associated with premenstrual symptoms in healthy …

Background: In many research settings, the intervention implied by the average causal effect
of a time-varying exposure is impractical or unrealistic, and we might instead prefer a more …