Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

DJ Lawson, NM Davies, S Haworth, B Ashraf, L Howe… - Human Genetics, 2020 - Springer
Replicable genetic association signals have consistently been found through genome-wide
association studies in recent years. The recent dramatic expansion of study sizes improves …

Pleiotropy, epistasis and the genetic architecture of quantitative traits

TFC Mackay, RRH Anholt - Nature Reviews Genetics, 2024 - nature.com
Pleiotropy (whereby one genetic polymorphism affects multiple traits) and epistasis
(whereby non-linear interactions between genetic polymorphisms affect the same trait) are …

[HTML][HTML] Large-scale genomic and transcriptomic analyses elucidate the genetic basis of high meat yield in chickens

X Tan, R Liu, D Zhao, Z He, W Li, M Zheng, Q Li… - Journal of advanced …, 2024 - Elsevier
Introduction Investigating the genetic markers and genomic signatures related to chicken
meat production by combing multi-omics methods could provide new insights into modern …

[图书][B] Population genetics and microevolutionary theory

AR Templeton - 2021 - books.google.com
Population Genetics and Microevolutionary Theory Explore the fundamentals of the
biological implications of population genetic theory In the newly revised Second Edition of …

Deep learning versus parametric and ensemble methods for genomic prediction of complex phenotypes

R Abdollahi-Arpanahi, D Gianola… - Genetics Selection …, 2020 - Springer
Background Transforming large amounts of genomic data into valuable knowledge for
predicting complex traits has been an important challenge for animal and plant breeders …

Genomic selection in plant breeding: Key factors shaping two decades of progress

A Alemu, J Åstrand, OA Montesinos-Lopez… - Molecular Plant, 2024 - cell.com
Genomic selection, the application of genomic prediction (GP) models to select candidate
individuals, has significantly advanced in the past two decades, effectively accelerating …

Benchmarking machine learning and parametric methods for genomic prediction of feed efficiency-related traits in Nellore cattle

LFM Mota, LM Arikawa, SWB Santos… - Scientific Reports, 2024 - nature.com
Genomic selection (GS) offers a promising opportunity for selecting more efficient animals to
use consumed energy for maintenance and growth functions, impacting profitability and …

Predicting male fertility in dairy cattle using markers with large effect and functional annotation data

JP Nani, FM Rezende, F Peñagaricano - BMC genomics, 2019 - Springer
Background Fertility is among the most important economic traits in dairy cattle. Genomic
prediction for cow fertility has received much attention in the last decade, while bull fertility …

Genomic Selection and Genome-wide Association Study for Feed-Efficiency Traits in a Farmed Nile Tilapia (Oreochromis niloticus) Population

A Barría, JAH Benzie, RD Houston… - Frontiers in …, 2021 - frontiersin.org
Nile tilapia is a key aquaculture species with one of the highest production volumes globally.
Genetic improvement of feed efficiency via selective breeding is an important goal, and …

Genomic prediction for commercial traits using univariate and multivariate approaches in Nile tilapia (Oreochromis niloticus)

R Joshi, A Skaarud, M de Vera, AT Alvarez, J Ødegård - Aquaculture, 2020 - Elsevier
Background Over the past three decades, Nile tilapia industry has grown into a significant
aquaculture industry spread over 120 tropical and sub-tropical countries around the world …