Biomaterials tools to modulate the tumour microenvironment in immunotherapy

Y Chao, Z Liu - Nature Reviews Bioengineering, 2023 - nature.com
Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

19F Magnetic Resonance Imaging (MRI): From Design of Materials to Clinical Applications

I Tirotta, V Dichiarante, C Pigliacelli, G Cavallo… - Chemical …, 2015 - ACS Publications
To enable early monitoring of various diseases, to develop noninvasive diagnostic tools,
and to implement targeted therapies are some of the major challenges in current medicine …

Enhanced photodynamic therapy for overcoming tumor hypoxia: From microenvironment regulation to photosensitizer innovation

J Du, T Shi, S Long, P Chen, W Sun, J Fan… - Coordination Chemistry …, 2021 - Elsevier
Photodynamic therapy (PDT) has garnered an increasing interest by both researchers and
clinicians as a non-invasive therapy that allows a selective treatment towards tumors …

Supramolecular hydrogels: Design strategies and contemporary biomedical applications

J Omar, D Ponsford, CA Dreiss… - Chemistry–An Asian …, 2022 - Wiley Online Library
Self‐assembly of supramolecular hydrogels is driven by dynamic, non‐covalent interactions
between molecules. Considerable research effort has been exerted to fabricate and …

Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Compositions and methods for molecular labeling

M Samuels, JC Olson, A Watson, K Brown… - US Patent …, 2015 - Google Patents
2012-05-08 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Biocompatible surfactants for water-in-fluorocarbon emulsions

C Holtze, AC Rowat, JJ Agresti, JB Hutchison… - Lab on a Chip, 2008 - pubs.rsc.org
Drops of water-in-fluorocarbon emulsions have great potential for compartmentalizing both
in vitro and in vivo biological systems; however, surfactants to stabilize such emulsions are …

The fluorous effect in biomolecular applications

M Cametti, B Crousse, P Metrangolo, R Milani… - Chemical Society …, 2012 - pubs.rsc.org
From being a niche area only a few decades ago, fluorous chemistry has gained momentum
and is, nowadays, a fervent area of research. It has brought forth, in fact, numerous …

Selected physicochemical aspects of poly-and perfluoroalkylated substances relevant to performance, environment and sustainability—Part one

MP Krafft, JG Riess - Chemosphere, 2015 - Elsevier
The elemental characteristics of the fluorine atom tell us that replacing an alkyl chain by a
perfluoroalkyl or polyfluorinated chain in a molecule or polymer is consequential. A brief …

α-Fluorinated ethers, thioethers, and amines: anomerically biased species

F Leroux, P Jeschke, M Schlosser - Chemical reviews, 2005 - ACS Publications
When asked to draw up a list of textbook substituents, hardly anyone would consider to
associate such an “exotic entity” like trifluoromethoxy to the lastingly popular carboxy, acetyl …