Highlights•Tissue damage recognition by myeloid cells shapes immune responses.•
Recognition of immunogenic cell death by myeloid cells promotes inflammation.•Myeloid …

Mincle (m acrophage in ducible C-type le ctin, Clec4e, Clecsf9) was originally identified as a
member of the C-type lectin receptor family in 1999. Then, the function of Mincle to control …

Abstract Background/Aim: Acute liver injury (ALI) is a life-threatening clinical syndrome that
is usually caused by toxic chemicals, drugs, or pathogen infections. Sirtuin2 (Sirt2), an NAD+ …

Concanavalin A (ConA) is a plant lectin that can induce immune-mediated liver damage.
ConA induced liver damage animal model is a widely accepted model that can mimic …

After both sterile and infectious insults, damage is inflicted on tissues leading to accidental
or programmed cell death. In addition, events of programmed cell death also take place …

In 2020, three articles were published on a protein that can activate the immune system by
binding to macrophage-inducible C-type lectin receptor (Mincle). In the articles, the protein …

The use of approved nomenclature in publications is vital to enable effective scientific
communication and is particularly crucial when discussing genes of clinical relevance. Here …

Autophagy activation is one of the survival mechanisms of ethanol-induced hepatitis in
mammals. Both Curcumin and Baicalin have anti-inflammatory effects, but the mechanism of …

Background: Cigarette smoke (CS) is a cause of premature death and exacerbates the
severity of diseases not only in lungs, but also in systemic organs having no direct contact …

目的: 研究丹皮酚对β-1, 3-葡聚糖诱导的巨噬细胞上Dectin-1/NLRP3 信号通路的影响. 方法:
培养小鼠RAW264. 7 巨噬细胞, 并分成空白对照组, β-1, 3-葡聚糖诱导模型组 …