Epidemiology and diagnostics of carbapenem resistance in gram-negative bacteria

P Nordmann, L Poirel - Clinical Infectious Diseases, 2019 - academic.oup.com
Carbapenem resistance in gram-negative bacteria has caused a global epidemic that
continues to grow. Although carbapenemase-producing Enterobacteriaceae have received …

Coronavirus disease 2019, superinfections, and antimicrobial development: what can we expect?

CJ Clancy, MH Nguyen - Clinical Infectious Diseases, 2020 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) arose at a time of great concern about
antimicrobial resistance (AMR). No studies have specifically assessed COVID-19 …

Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital‐acquired infections: a scientific review

M Nguyen, SG Joshi - Journal of applied microbiology, 2021 - academic.oup.com
Carbapenem is an important therapy for serious hospital‐acquired infections and for the
care of patients affected by multidrug‐resistant organisms, specifically Acinetobacter …

Bloodstream infections in critically ill patients: an expert statement

JF Timsit, E Ruppé, F Barbier, A Tabah… - Intensive care medicine, 2020 - Springer
Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii

M Hamidian, SJ Nigro - Microbial genomics, 2019 - microbiologyresearch.org
Acinetobacter baumannii is a nosocomial pathogen that has emerged as a global threat
because of high levels of resistance to many antibiotics, particularly those considered to be …

[HTML][HTML] Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy

J Ma, X Song, M Li, Z Yu, W Cheng, Z Yu… - Microbiological …, 2023 - Elsevier
Bacterial drug resistance has become a global public health threat, among which the
infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable …

Epidemiology and mechanisms of resistance of extensively drug resistant Gram-negative bacteria

EM Eichenberger, JT Thaden - Antibiotics, 2019 - mdpi.com
Antibiotic resistance has increased markedly in gram-negative bacteria over the last two
decades, and in many cases has been associated with increased mortality and healthcare …

Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments

EC Eze, HY Chenia, ME El Zowalaty - Infection and drug …, 2018 - Taylor & Francis
Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …

Rationalizing antimicrobial therapy in the ICU: a narrative review

JF Timsit, M Bassetti, O Cremer, G Daikos… - Intensive care …, 2019 - Springer
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

Novel Plasmid-Mediated tet(X5) Gene Conferring Resistance to Tigecycline, Eravacycline, and Omadacycline in a Clinical Acinetobacter baumannii Isolate

L Wang, D Liu, Y Lv, L Cui, Y Li, T Li… - Antimicrobial agents …, 2019 - Am Soc Microbiol
ABSTRACT A novel, plasmid-mediated, high-level tigecycline resistance tet (X) gene
variant, tet (X5), was detected in a clinical Acinetobacter baumannii isolate from China in …