Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Applications of inorganic nanomaterials in photothermal therapy based on combinational cancer treatment

J Wang, X Wu, P Shen, J Wang, Y Shen… - International Journal …, 2020 - Taylor & Francis
Background Cancer is one of the major causes of death and is difficult to cure using existing
clinical therapies. Clinical cancer treatments [such as surgery, chemotherapy (CHT) …

Exosome-based tumor antigens–adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA

M Morishita, Y Takahashi, A Matsumoto, M Nishikawa… - Biomaterials, 2016 - Elsevier
For cancer immunotherapy via tumor antigen vaccination in combination with an adjuvant,
major challenges include the identification of a particular tumor antigen and efficient delivery …

Combinatorial photothermal and immuno cancer therapy using chitosan-coated hollow copper sulfide nanoparticles

L Guo, DD Yan, D Yang, Y Li, X Wang, O Zalewski… - ACS …, 2014 - ACS Publications
Near-infrared light-responsive inorganic nanoparticles have been shown to enhance the
efficacy of cancer photothermal ablation therapy. However, current nanoparticle-mediated …

Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

DS Watson, AN Endsley, L Huang - Vaccine, 2012 - Elsevier
Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

[HTML][HTML] RNA nanotechnology-mediated cancer immunotherapy

YX Lin, Y Wang, S Blake, M Yu, L Mei, H Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
RNA molecules (eg, siRNA, microRNA, and mRNA) have shown tremendous potential for
immunomodulation and cancer immunotherapy. They can activate both innate and adaptive …

Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and co-delivery platform for enhanced cancer immunotherapy

Y Lu, Y Yang, Z Gu, J Zhang, H Song, G Xiang, C Yu - Biomaterials, 2018 - Elsevier
Silica based nanoparticles have emerged as a promising vaccine delivery system for cancer
immunotherapy, but their bio-degradability, adjuvanticity and the resultant antitumor activity …

Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system

N Hanagata - International journal of nanomedicine, 2012 - Taylor & Francis
Unmethylated cytosine-phosphate-guanosine (CpG) oligodeoxynucleotides (ODNs) are
recognized by Toll-like receptor 9 (TLR9) found in antigen-presenting cells and B cells and …

CpG oligodeoxynucleotides for anticancer monotherapy from preclinical stages to clinical trials

Z Zhang, JCT Kuo, S Yao, C Zhang, H Khan, RJ Lee - Pharmaceutics, 2021 - mdpi.com
CpG oligodeoxynucleotides (CpG ODNs), the artificial versions of unmethylated CpG motifs
that were originally discovered in bacterial DNA, are demonstrated not only as potent …

Polyvalent immunostimulatory nanoagents with self‐assembled CpG oligonucleotide‐conjugated gold nanoparticles

M Wei, N Chen, J Li, M Yin, L Liang, Y He, H Song… - Angewandte …, 2012 - infona.pl
Transportvehikel: Gold‐Nanopartikel (AuNPs) werden als Träger für die nichtinvasive
Einschleusung von synthetischen Cytosinphosphatguanosin (CpG) …