[HTML][HTML] The interplay between gut microbiota and Parkinson's disease: Implications on diagnosis and treatment

A Varesi, LIM Campagnoli, F Fahmideh… - International journal of …, 2022 - mdpi.com
The bidirectional interaction between the gut microbiota (GM) and the Central Nervous
System, the so-called gut microbiota brain axis (GMBA), deeply affects brain function and …

[HTML][HTML] The involvement of neuroinflammation in the onset and progression of Parkinson's disease

A Jurcau, FL Andronie-Cioara… - International Journal of …, 2023 - mdpi.com
Parkinson's disease is a neurodegenerative disease exhibiting the fastest growth in
incidence in recent years. As with most neurodegenerative diseases, the pathophysiology is …

Alpinetin inhibits neuroinflammation and neuronal apoptosis via targeting the JAK2/STAT3 signaling pathway in spinal cord injury

S Xiao, Y Zhang, Z Liu, A Li, W Tong… - CNS neuroscience & …, 2023 - Wiley Online Library
Background A growing body of research shows that drug monomers from traditional
Chinese herbal medicines have antineuroinflammatory and neuroprotective effects that can …

[HTML][HTML] The role of the CD8+ T cell compartment in ageing and neurodegenerative disorders

E Terrabuio, E Zenaro, G Constantin - Frontiers in Immunology, 2023 - frontiersin.org
CD8+ lymphocytes are adaptive immunity cells with the particular function to directly kill the
target cell following antigen recognition in the context of MHC class I. In addition, CD8+ T …

[HTML][HTML] Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration

D Mannino, SA Scuderi, G Casili, V Bova… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal
neurons, which causes disabling motor disorders. Scientific findings support the role of …

[Retracted] Role of Glial Cell‐Derived Oxidative Stress in Blood‐Brain Barrier Damage after Acute Ischemic Stroke

X Hu, Y Wang, W Du, LJ Liang… - … Medicine and Cellular …, 2022 - Wiley Online Library
The integrity of the blood‐brain barrier (BBB) is mainly maintained by endothelial cells and
basement membrane and could be regulated by pericytes, neurons, and glial cells including …

[HTML][HTML] Zinc homeostasis: an emerging therapeutic target for neuroinflammation related diseases

S Liu, N Wang, Y Long, Z Wu, S Zhou - Biomolecules, 2023 - mdpi.com
Zinc is an indispensable trace element in the human body and plays an important role in
regulating normal growth and development. Zinc homeostasis in the central nervous system …

A novel synthetic peptide SVHRSP attenuates dopaminergic neurodegeneration by inhibiting NADPH oxidase-mediated neuroinflammation in experimental models of …

X Zhang, D Tu, S Li, N Li, D Li, Y Gao, L Tian… - Free Radical Biology …, 2022 - Elsevier
Current treatment of Parkinson's disease (PD) ameliorates symptoms but fails to block
disease progression. This study was conducted to explore the protective effects of SVHRSP …

Microglia‐Mediated Neuroimmune Response Regulates Cardiac Remodeling After Myocardial Infarction

M Wang, J Zhang, Z Yin, W Ding, M Zhao… - Journal of the …, 2023 - Am Heart Assoc
Background Sympathetic hyperactivity contributes to pathological remodeling after
myocardial infarction (MI). However, the mechanisms underlying the increase in sympathetic …

[HTML][HTML] Targeting the blood–brain barrier to delay aging-accompanied neurological diseases by modulating gut microbiota, circadian rhythms, and their interplays

Y Wang, W Du, X Hu, X Yu, C Guo, X Jin… - … Pharmaceutica Sinica B, 2023 - Elsevier
The blood–brain barrier (BBB) impairment plays a crucial role in the pathological processes
of aging-accompanied neurological diseases (AAND). Meanwhile, circadian rhythms …