Long non-coding RNAs in the regulation of gene expression: physiology and disease

JCR Fernandes, SM Acuña, JI Aoki, LM Floeter-Winter… - Non-coding RNA, 2019 - mdpi.com
The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …

Exosomes: biogenesis, biologic function and clinical potential

Y Zhang, Y Liu, H Liu, WH Tang - Cell & bioscience, 2019 - Springer
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …

Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment

Z Sun, S Yang, Q Zhou, G Wang, J Song, Z Li, Z Zhang… - Molecular cancer, 2018 - Springer
Exosomes are extracellular vesicles released by many cell types and have been attributed
for their roles in many diseases including cancer. Exosomes secreted by tumor cells and …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology

A Yokoi, T Ochiya - Seminars in cancer biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …

Tumor cells derived-exosomes as angiogenenic agents: possible therapeutic implications

M Ahmadi, J Rezaie - Journal of translational medicine, 2020 - Springer
Angiogenesis is a multistep process and various molecules are involved in regulating it.
Extracellular vesicles are cell-derived particles, secreted from several types of cells and are …

[HTML][HTML] To protect and to preserve: novel preservation strategies for extracellular vesicles

GD Kusuma, M Barabadi, JL Tan… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by
stem cells exert similar therapeutic effects and these have been proposed as an alternative …

Exosomal circHIPK3 released from hypoxia‐pretreated cardiomyocytes regulates oxidative damage in cardiac microvascular endothelial cells via the miR‐29a/IGF‐1 …

Y Wang, R Zhao, W Liu, Z Wang, J Rong… - Oxidative medicine …, 2019 - Wiley Online Library
Background/Aims. Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs
that regulate gene expression in eukaryotes. Recently, exosomes from cardiomyocytes …

Unpacking extracellular vesicles: RNA cargo loading and function

ER Dellar, C Hill, GE Melling… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are a heterogeneous group of membrane‐enclosed structures
produced by prokaryotic and eukaryotic cells. EVs carry a range of biological cargoes …

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

H Sork, G Corso, K Krjutskov, HJ Johansson… - Scientific reports, 2018 - nature.com
Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …