The architectural dynamics of the bacterial flagellar motor switch
S Khan - Biomolecules, 2020 - mdpi.com
The rotary bacterial flagellar motor is remarkable in biochemistry for its highly synchronized
operation and amplification during switching of rotation sense. The motor is part of the …
operation and amplification during switching of rotation sense. The motor is part of the …
Control of acetyl phosphate-dependent phosphorylation of the response regulator CiaR by acetate kinase in Streptococcus pneumoniae
S Kaiser, LM Hoppstädter, K Bilici, K Heieck… - …, 2020 - microbiologyresearch.org
The two-component regulatory system CiaRH of Streptococcus pneumoniae affects a large
variety of physiological processes including ß-lactam resistance, competence development …
variety of physiological processes including ß-lactam resistance, competence development …
Gram-negative bacteria resist antimicrobial agents by a DzrR-mediated envelope stress response
Z Liang, Q Lin, Q Wang, L Huang, H Liu, Z Shi, Z Cui… - BMC biology, 2023 - Springer
Abstract Background Envelope stress responses (ESRs) are critical for adaptive resistance
of Gram-negative bacteria to envelope-targeting antimicrobial agents. However, ESRs are …
of Gram-negative bacteria to envelope-targeting antimicrobial agents. However, ESRs are …
The W-Acidic Motif of Histidine Kinase WalK Is Required for Signaling and Transcriptional Regulation in Streptococcus mutans
L Kong, M Su, J Sang, S Huang, M Wang… - Frontiers in …, 2022 - frontiersin.org
In Streptococcus mutans, we find that the histidine kinase WalK possesses the longest C-
terminal tail (CTT) among all 14 TCSs, and this tail plays a key role in the interaction of WalK …
terminal tail (CTT) among all 14 TCSs, and this tail plays a key role in the interaction of WalK …
Structure of Phosphorylated-like ClpXP Adaptor RssB Reveals an Interface Switch for Activation
C Brugger, J Schwartz, M Filipovski, AM Deaconescu - bioRxiv, 2022 - biorxiv.org
In γ-proteobacteria such as Escherichia coli, the general stress response is mediated by σs,
the stationary phase dissociable promoter specificity subunit of RNA polymerase. σs is …
the stationary phase dissociable promoter specificity subunit of RNA polymerase. σs is …
Predicted Functional and Structural Diversity of Receiver Domains in Fungal Two-Component Regulatory Systems
Fungal two-component regulatory systems incorporate receiver domains into hybrid
histidine kinases (HHKs) and response regulators. We constructed a nonredundant …
histidine kinases (HHKs) and response regulators. We constructed a nonredundant …
The Solvation of the E. coli CheY Phosphorylation Site Mapped by XFMS
M Hamid, MF Khalid, SU Chaudhary… - International Journal of …, 2022 - mdpi.com
The Escherichia coli CheY protein belongs to a large bacterial response regulator
superfamily. X-ray hydroxy radical foot-printing with mass spectroscopy (XFMS) has shown …
superfamily. X-ray hydroxy radical foot-printing with mass spectroscopy (XFMS) has shown …
Low phosphatase activity of LiaS and strong LiaR-DNA affinity explain the unusual LiaS to LiaR in vivo stoichiometry
S Jani, K Sterzenbach, V Adatrao, G Tajbakhsh… - BMC microbiology, 2020 - Springer
Abstract Background LiaRS mediates Bacillus subtilis response to cell envelope
perturbations. A third protein, LiaF, has an inhibitory role over LiaRS in the absence of …
perturbations. A third protein, LiaF, has an inhibitory role over LiaRS in the absence of …
The heme precursor 5-aminolevulinic acid triggers the shutdown of the HemKR signalling system in Leptospira
JA Imelio, F Trajtenberg, S Mondino, L Zarantonelli… - bioRxiv, 2023 - biorxiv.org
Two–component systems (TCSs) sense specific signals, regulating countless physiological
pathways. Heme concentrations are kept at defined levels in cells by means of exquisite …
pathways. Heme concentrations are kept at defined levels in cells by means of exquisite …