[HTML][HTML] Multiscale QM/MM modelling of catalytic systems with ChemShell

Y Lu, K Sen, C Yong, DSD Gunn, JA Purton… - Physical Chemistry …, 2023 - pubs.rsc.org
Hybrid quantum mechanical/molecular mechanical (QM/MM) methods are a powerful
computational tool for the investigation of all forms of catalysis, as they allow for an accurate …

[HTML][HTML] Red light optogenetics in neuroscience

K Lehtinen, MS Nokia, H Takala - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …

[HTML][HTML] Light-regulated gene expression in Bacteria: Fundamentals, advances, and perspectives

R Ohlendorf, A Möglich - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …

A thermal-stable Mn4+-doped far-red-emitting phosphor-converted LED for indoor plant cultivation

K Deng, Y Jin, L Yuan, B Wang, H Wu, Y Hu - Materials Today Chemistry, 2022 - Elsevier
Artificial light-emitting diode (LED) light source, regarded as a front-runner technology for the
promoting of plant growth, has attracted much attention toward the burgeoning fertilizer-free …

Engineering bacteriophytochrome-coupled photoactivated adenylyl cyclases for enhanced optogenetic camp modulation

Q Xu, A Vogt, F Frechen, C Yi, M Küçükerden… - Journal of molecular …, 2024 - Elsevier
Sensory photoreceptors abound in nature and enable organisms to adapt behavior,
development, and physiology to environmental light. In optogenetics, photoreceptors allow …

Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors

M Hörner, C Jerez-Longres, A Hudek, S Hook… - Science …, 2021 - science.org
Methodologies for the controlled delivery of genetic information into target cells are of utmost
importance for genetic engineering in both fundamental and applied research. However …

Ultra-short laser pulses propagation through mouse head tissues: experimental and computational study

D Galiakhmetova, V Dremin, A Koviarov… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
We present a prototype and verification of a multichannel laser system applicable to
optogenetic research. In vivo photostimulation of neural cells expressing photoconvertible …

Comparison of nonlinear properties of monomer and dimer of bacterial phytochrome from Deinococcus radiodurans

DI Galiakhmetova, AS Koviarov, VV Dremin… - … on Biomedical Optics, 2023 - opg.optica.org
Current medicine might be greatly enhanced by the ability to in vivo control and monitor
neurons using opsins/phytochromes expressed in neural cells. The fundamental challenge …

Evaluation of penetration depth of near-infrared irradiation generated by tunable ultra-short pulsed laser in ex vivo samples of mouse head

D Galiakhmetova, V Dremin, A Koviarov… - Tissue Optics and …, 2022 - spiedigitallibrary.org
Optogenetic research has opened up the possibility to control neurons that will help detect
and treat neurological diseases in the early stage. Treatment of dysfunctions requires …