Fragile X syndrome (FXS) is a neurodevelopmental disorder that causes intellectual
disability. It is a leading known genetic cause of autism. In addition to cognitive, social, and …

A key question in systems neuroscience is to identify how sensory stimuli are represented in
neuronal activity, and how the activity of sensory neurons in turn is “read out” by downstream …

In the mammalian brain, sensory cortices exhibit plasticity during task learning, but how this
alters information transferred between connected cortical areas remains unknown. We found …

When a neuron responds to a sensory stimulus, two fundamental codes [1–6] may transmit
the information specifying stimulus identity—spike rate (the total number of spikes in the …

The neuronal mechanisms generating a delayed motor response initiated by a sensory cue
remain elusive. Here, we tracked the precise sequence of cortical activity in mice …

Touch perception depends on integrating signals from multiple types of peripheral
mechanoreceptors. Merkel-cell associated afferents are thought to play a major role in form …

HIV/AIDS remains a major global public health issue. While antiretroviral therapy is effective
at reducing the viral load in the blood, up to 50% of those with HIV suffer from some degree …

Many brain areas modulate their activity during vibrotactile tasks. The activity from these
areas may code the stimulus parameters, stimulus perception, or perceptual reports. Here …

In addition to cognitive impairments, neurodevelopmental disorders often result in sensory
processing deficits. However, the biological mechanisms that underlie impaired sensory …

It has long been posited that detectability of sensory inputs can be sacrificed in favor of
improved discriminability and that sensory adaptation may mediate this trade-off. The extent …