Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?

MS Cohen, MK Smith, KE Muessig, TB Hallett… - The Lancet, 2013 - thelancet.com
Antiretroviral drugs that inhibit viral replication were expected to reduce transmission of HIV
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …

Preexposure prophylaxis for HIV prevention: where have we been and where are we going?

JM Baeten, JE Haberer, AY Liu… - JAIDS Journal of Acquired …, 2013 - journals.lww.com
Preexposure prophylaxis (PrEP), in which HIV-uninfected persons with ongoing HIV risk use
antiretroviral medications to reduce their risk of acquiring HIV infection, is an efficacious and …

[HTML][HTML] Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label …

S McCormack, DT Dunn, M Desai, DI Dolling, M Gafos… - The Lancet, 2016 - thelancet.com
Background Randomised placebo-controlled trials have shown that daily oral pre-exposure
prophylaxis (PrEP) with tenofovir–emtricitabine reduces the risk of HIV infection. However …

Illicit drug use in sexual settings ('chemsex') and HIV/STI transmission risk behaviour among gay men in South London: findings from a qualitative study

A Bourne, D Reid, F Hickson, S Torres-Rueda… - Sexually transmitted …, 2015 - sti.bmj.com
Background 'Chemsex'is a colloquial term used in the UK that describes sex under the
influence of psychoactive substances (typically crystal methamphetamine, mephedrone and …

Sexualized drug use ('chemsex') and high‐risk sexual behaviours in HIV‐positive men who have sex with men

EL Pufall, M Kall, M Shahmanesh, A Nardone… - HIV …, 2018 - Wiley Online Library
Objectives The incidence of sexually transmitted infections (STI s) and HIV infection remains
high in gay, bisexual, and other men who have sex with men (MSM) in the UK, and …

[HTML][HTML] Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain: findings from the National Surveys of Sexual Attitudes and …

P Sonnenberg, S Clifton, S Beddows, N Field, K Soldan… - The Lancet, 2013 - thelancet.com
Background Population-based estimates of prevalence, risk distribution, and intervention
uptake inform delivery of control programmes for sexually transmitted infections (STIs). We …

Poly drug use, chemsex drug use, and associations with sexual risk behaviour in HIV-negative men who have sex with men attending sexual health clinics

J Sewell, A Miltz, FC Lampe, V Cambiano… - International Journal of …, 2017 - Elsevier
Background Recreational drug use and associated harms continue to be of significant
concern in men who have sex with men (MSM) particularly in the context of HIV and STI …

Trends in condom use among MSM in the United States: the role of antiretroviral therapy and seroadaptive strategies

G Paz-Bailey, MCB Mendoza, T Finlayson, C Wejnert… - Aids, 2016 - journals.lww.com
Objective: Evaluate changes in condomless anal sex at last sex among men who have sex
with men (MSM) and assess if these changes are associated with the adoption of …

[HTML][HTML] Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 …

JW Eaton, NA Menzies, J Stover… - The Lancet Global …, 2014 - thelancet.com
Background New WHO guidelines recommend initiation of antiretroviral therapy for HIV-
positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was …

[HTML][HTML] Cost-effectiveness of pre-exposure prophylaxis for HIV prevention in men who have sex with men in the UK: a modelling study and health economic …

V Cambiano, A Miners, D Dunn… - The Lancet infectious …, 2018 - thelancet.com
Summary Background In the UK, HIV incidence among men who have sex with men (MSM)
has remained high for several years, despite widespread use of antiretroviral therapy and …