The popularity of hydrogels as biomaterials lies in their tunable physical properties, ability to
encapsulate small molecules and macromolecular drugs, water holding capacity, flexibility …

Polymers from natural sources are widely used as excipients in the formulation of
pharmaceutical dosage forms. The objective of this study was to extract and further …

In situ gels have been extensively explored as ocular drug delivery system to enhance
bioavailability and efficacy. The objective of present study was to design, formulate and …

The low aqueous solubility and permeability of apremilast restricted its clinical efficiency in
oral therapy for psoriasis arthritis. This research aimed to develop nanosized lipid carrier …

Transdermal delivery of insulin is a great challenge due to its poor permeability through the
skin. The aim of the current investigation was to evaluate the prospective of insulin loaded …

Rasagiline mesylate is used as first line agent for early management of Parkinson's disease
but its water soluble nature creates hurdles to cross blood brain barrier also its low oral …

Rivastigmine, a reversible cholinesterase inhibitor, is frequently indicated in the
management of demented conditions associated with Alzheimer disease. The major hurdle …

Poor aqueous solubility besides extensive hepatic first effect significantly decreases the oral
absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes …

Diabetic foot infection (DFI) is an important cause of morbidity and mortality. Antibiotics are
fundamental for treating DFI, although bacterial biofilm formation and associated …

Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs
through the thick multi-layered keratinized nail plate. The objective of this investigation was …