Aquaporins (AQP) are a class of water channel membrane proteins that are widely
expressed in the gut. The biological functions of aquaporins, which regulate the absorption …

Constipation is a prevalent clinical ailment of the gastrointestinal system, yet its
pathogenesis remains ambiguous. Despite the availability of numerous treatment …

Ethnopharmacological relevance The leaf of Moringa oleifera Lam., a medicinal and edible
herb for thousands of years in Ayurveda, is used as Pancha (na) karma (purgative) during …

The present study aimed to investigate the effect of oral administration of snail-derived
mucin extract (SM) on ameliorating constipation symptoms of loperamide-induced …

Several types of saponins and herbal plants containing saponins have been reported to
have anti-inflammatory or laxative activities. To verify the therapeutic effects of saponin …

Iron is an essential element in the central nervous system that is involved in many of its
important biological processes, such as oxygen transportation, myelin production, and …

Indirect evidence has determined the possibility that microplastics (MP) induce constipation,
although direct scientific proof for constipation induction in animals remains unclear. To …

To investigate the role of tannin-enriched extracts of Ecklonia cava (TEE) on the regulation
of oxidative balance and laxative activity in chronic constipation, we investigated alterations …

Researches on spicatoside A (SpiA)-containing natural products suggest the possibility of
SpiA as a potential laxative to alleviate chronic constipation. However, no studies have been …

Red Liriope platyphylla (RLP) is a known herbal medicine used in the treatment of some
chronic diseases including constipation, neurodegenerative disorders, diabetes and obesity …