The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

The intranasal route has been receiving greater attention from the scientific community not
only for systemic drug delivery but also for the treatment of pulmonary and neurological …

Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …

Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Recalcitrant respiratory tract infections caused by bacteria have emerged as one of the
greatest health challenges worldwide. Aerosolized antimicrobial therapy is becoming …

Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …

The surfaces of human internal organs are lined by a mucus layer that ensures symbiotic
relationships with commensal microbiome while protecting against potentially injurious …

Since most current studies have focused on exploring how phagocyte internalization of drug-
loaded nanovesicles by macrophages would affect the function and therapeutic effects of …

Organic cation transporters (OCT) 1, 2 and 3 and novel organic cation transporters (OCTN) 1
and 2 of the solute carrier 22 (SLC22) family are involved in the cellular transport of …

Pulmonary delivery has gained increased interests over the past few decades. For
conditions within the respiratory tract, targeted drug delivery directly to the site of action can …