Mechanisms of retention of PEGylated recombinant human deoxyribonuclease i (rhDNase) in the lungs

S Mahri - 2020 - eprints.nottingham.ac.uk
Conjugation of recombinant human deoxyribonuclease I (rhDNase) to large (≥ 20 kDa)
polyethylene glycol (PEG) has been shown to prolong the lung residence time of the …

[PDF][PDF] The influence of mucus on the permeability of inhalable APIs

S Radivojev, L Kargl, C Meindl, JT Pinto… - … A: Analytics I - pssrc-symposium.com
PURPOSE Many possibilities have been recognized in the use of inhalation as a route for
the delivery of drugs. Nevertheless, the invitro methods that are commonly used for other …