Early-life programming of adipose tissue

E Moreno-Mendez, S Quintero-Fabian… - Nutrition Research …, 2020 - cambridge.org
Worldwide obesity is increasing at an alarming rate in children and adolescents, with the
consequent emergence of co-morbidities. Moreover, the maternal environment during …

Neurodevelopmental programming of adiposity: contributions to obesity risk

AA Skowronski, RL Leibel, CA LeDuc - Endocrine Reviews, 2024 - academic.oup.com
This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …

[HTML][HTML] Biomonitoring of bisphenol A concentrations in maternal and umbilical cord blood in regard to birth outcomes and adipokine expression: a birth cohort study in …

WC Chou, JL Chen, CF Lin, YC Chen, FC Shih… - Environmental …, 2011 - Springer
Abstract Background Bisphenol A (BPA) is a sealant and flux of plastic materials and has
been determined to be an endocrine-disrupting chemical. Prenatal exposure to BPA can …

Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors

C Lesseur, DA Armstrong, AG Paquette… - Molecular and cellular …, 2013 - Elsevier
Leptin a regulator of body weight is involved in reproductive and developmental functions.
Leptin promoter DNA methylation (LEP) regulates gene expression in a tissue-specific …

[HTML][HTML] A birth cohort study to investigate the association between prenatal phthalate and bisphenol A exposures and fetal markers of metabolic dysfunction

J Ashley-Martin, L Dodds, TE Arbuckle, AS Ettinger… - Environmental …, 2014 - Springer
Background Obesity and type-2 diabetes are on the rise and in utero exposure to
environmental contaminants is a suspected contributing factor. Our objective was to …

Associations of perfluoroalkyl substances with adipocytokines in umbilical cord serum: a mixtures approach

J Ding, Y Dai, J Zhang, Z Wang, L Zhang, S Xu… - Environmental …, 2023 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS), a kind of emerging environmental
endocrine disruptors, may interfere with the secretion of adipokines and affect fetal …

[HTML][HTML] Metabolic markers during pregnancy and their association with maternal and newborn weight status

O Perichart-Perera, C Muñoz-Manrique… - PLoS …, 2017 - journals.plos.org
Background/Aims Obesity during pregnancy increases the risk of adverse clinical outcomes
and is associated with low-grade chronic inflammation. We describe maternal metabolic risk …

[HTML][HTML] Maternal psychiatric disease and epigenetic evidence suggest a common biology for poor fetal growth

TH Ciesielski, CJ Marsit, SM Williams - BMC pregnancy and childbirth, 2015 - Springer
Background We sought to identify and characterize predictors of poor fetal growth among
variables extracted from perinatal medical records to gain insight into potential etiologic …

[HTML][HTML] The postnatal leptin surge in mice is variable in both time and intensity and reflects nutritional status

AA Skowronski, ED Shaulson, RL Leibel… - International Journal of …, 2022 - nature.com
Background/objectives The murine postnatal leptin surge occurs within the first 4 weeks of
life and is critical for neuronal projection development within hypothalamic feeding circuits …

[HTML][HTML] Significance of Umbilical Cord Leptin Profile during Pregnancy in Gestational Diabetes Mellitus—A Systematic Review and Meta-Analysis

MM Roca-Rodríguez, P Ramos-García… - Journal of Clinical …, 2023 - mdpi.com
Background: The literature provides limited evidence of cord blood leptin levels in
gestational diabetes mellitus (GDM), with contradictory and inconsistent results with respect …