Stroke is the leading cause of disability and mortality in the world, but the pathogenesis of
ischemic stroke (IS) is not completely clear and treatments are limited. Mounting evidence …

CC motif chemokine ligand 2 (CCL2) is a member of the monocyte chemokine protein
family, which binds to its receptor CCR2 to induce monocyte infiltration and mediate …

Future research would benefit from greater implementation of analytical and design-based
approaches to robustly model the alcohol use-dementia relationship in the general …

Binge or chronic alcohol consumption causes neuroinflammation and leads to alcohol use
disorder (AUD). AUD not only affects the central nervous system (CNS) but also leads to …

Alcohol consumption is known to cause several brain anomalies. The pathophysiological
changes associated with alcohol intoxication are mediated by various factors, most notable …

Alzheimer's disease is a progressive neurological disorder characterized by cognitive
decline and chronic inflammation within the brain. The ketogenic diet, a widely recognized …

Renal fibrosis is a common pathological manifestation in various chronic kidney diseases.
Inflammation plays a central role in renal fibrosis development. Owing to their significant …

Excessive alcohol use disrupts neuroimmune signaling across various cell types, including
neurons, microglia, and astrocytes. The present review focuses on recent, albeit limited …

Microglia are immune cells of the central nervous system that mediate neuroinflammation. It
is widely known that microglia-mediated inflammation in the brain contribute to the …

The central nervous system is vulnerable to chronic alcohol abuse, and alcohol dependence
is a chronically relapsing disorder which causes a variety of physical and mental disorders …